Crystallization of citrate-stabilized amorphous calcium phosphate to nanocrystalline apatite: A surface-mediated transformation

Konstantinos Chatzipanagis, Michele Iafisco, Teresa Roncal-Herrero, Matthew Bilton, Anna Tampieri, Roland Kröger, José Manuel Delgado-López

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

This work explores the mechanisms underlying the crystallization of citrate-functionalized amorphous calcium phosphate (cit-ACP) in two relevant media, combining in situ and ex situ characterization techniques. Results demonstrate that citrate desorption from cit-ACP triggers the surface-mediated transformation to nanocrystalline apatite (Ap). Our findings shed light on the key role of citrate, an important component of bone organic matrix, and the medium composition in controlling the rate of transformation and the morphology of the resulting Ap phase.

Original languageEnglish (US)
Pages (from-to)3170-3173
Number of pages4
JournalCrystEngComm
Volume18
Issue number18
DOIs
StatePublished - 2016

ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Science(all)
  • Condensed Matter Physics

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