Crystallinity in apatites: How can a truly disordered fraction be distinguished from nanosize crystalline domains?

Giancarlo Celotti, Anna Tampieri, Simone Sprio, Elena Landi, Luca Bertinetti, Gianmario Martra, Caterina Ducati

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

In the last decade synthetic apatites mimicking the human natural one have been widely prepared and characterized from the physico-chemical point of view; however a shading zone is still remaining related to the evaluation and distinction of the less crystalline part, almost amorphous, and the crystallographically well ordered, nano-sized part, inside the apatite itself. Actually natural apatite forming bone tissue can include both types of crystals whose prevalence is dependent from the specific bone evolution stage and the specialized tissue performance. The quantitative description of such a combination usually represents a puzzling problem, but the result can also clarify the definition of "crystallinity in apatite" that appears still controversial. Many different synthetic apatites, including those nucleated on organic templates, were analyzed with different techniques (X-ray diffraction, transmission electron microscopy, and so on) to clarify the true nature of the disordered part. The results, manipulated by the classical methodologies devised for substances with highly perturbed structural order, led to establish that only specifically prepared amorphous calcium phosphate is really a glass, while the distorted portion coexisting with more or less crystalline regions is simply nanocrystalline. Moreover, at the conceptual limit of crystallinity tending to zero, the two models surprisingly cease to be conflicting.

Original languageEnglish (US)
Pages (from-to)1079-1087
Number of pages9
JournalJournal of Materials Science: Materials in Medicine
Volume17
Issue number11
DOIs
StatePublished - Nov 1 2006

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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