Cranialization of the frontal sinus for secondary mucocele prevention following open surgery for benign frontal lesions

Gilad Horowitz, Moran Amit, Oded Ben-Ari, Ziv Gil, Abraham Abergel, Nevo Margalit, Oren Cavel, Oshri Wasserzug, Dan M. Fliss

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Objective: To compare frontal sinus cranialization to obliteration for future prevention of secondary mucocele formation following open surgery for benign lesions of the frontal sinus. Study Design: Retrospective case series. Setting: Tertiary academic medical center. Patients: Sixty-nine patients operated for benign frontal sinus pathology between 1994 and 2011. Interventions: Open excision of benign frontal sinus pathology followed by either frontal obliteration (n = 41, 59%) or frontal cranialization (n = 28, 41%). Main Outcome Measures: The prevalence of post-surgical complications and secondary mucocele formation were compiled. Results: Pathologies included osteoma (n = 34, 49%), mucocele (n = 27, 39%), fibrous dysplasia (n = 6, 9%), and encephalocele (n = 2, 3%). Complications included skin infections (n = 6), postoperative cutaneous fistula (n = 1), telecanthus (n = 4), diplopia (n = 3), nasal deformity (n = 2) and epiphora (n = 1). None of the patients suffered from postoperative CSF leak, meningitis or pneumocephalus. Six patients, all of whom had previously undergone frontal sinus obliteration, required revision surgery due to secondary mucocele formation. Statistical analysis using non-inferiority test reveal that cranialization of the frontal sinus is non-inferior to obliteration for preventing secondary mucocele formation (P<0.0001). Conclusion: Cranialization of the frontal sinus appears to be a good option for prevention of secondary mucocele development after open excision of benign frontal sinus lesions.

Original languageEnglish (US)
Article numbere83820
JournalPLoS ONE
Volume8
Issue number12
DOIs
StatePublished - Dec 23 2013

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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