Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female

Cailin O'Connell; Sylvia Jang; Paloma Monroig-Bosque; Anne Alaniz

doi:10.1016/j.gore.2023.101207

Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female

Cailin O'Connell, Sylvia Jang, Paloma Monroig-Bosque, Anne Alaniz

Research output: Contribution to journal › Article › peer-review

Abstract

•Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential.•Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy.•Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a collision tumor.•Alpha-fetoprotein can be trended over time to gauge response to treatment of cancers that produce the protein.

Original language	English (US)
Article number	101207
Pages (from-to)	101207
Journal	Gynecologic Oncology Reports
Volume	47
DOIs	https://doi.org/10.1016/j.gore.2023.101207
State	Published - Jun 2023

Keywords

Alpha-fetoprotein
Endometrial carcinoma
Endometroid
Hepatoid
Uterine cancer
Yolk sac tumor

ASJC Scopus subject areas

Oncology
Obstetrics and Gynecology

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10.1016/j.gore.2023.101207

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O'Connell, C., Jang, S., Monroig-Bosque, P., & Alaniz, A. (2023). Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female. Gynecologic Oncology Reports, 47, 101207. Article 101207. https://doi.org/10.1016/j.gore.2023.101207

Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female. / O'Connell, Cailin; Jang, Sylvia; Monroig-Bosque, Paloma et al.
In: Gynecologic Oncology Reports, Vol. 47, 101207, 06.2023, p. 101207.

Research output: Contribution to journal › Article › peer-review

O'Connell, C, Jang, S, Monroig-Bosque, P & Alaniz, A 2023, 'Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female', Gynecologic Oncology Reports, vol. 47, 101207, pp. 101207. https://doi.org/10.1016/j.gore.2023.101207

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title = "Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female",

abstract = "•Alpha-fetoprotein secreting tumors in gynecologic cancers have a broad differential.•Surgical pathology may provide a more comprehensive picture of tumor heterogeneity than initial biopsy.•Yolk Sac Tumor components intermixed with carcinoma points towards a somatic derivative rather than a collision tumor.•Alpha-fetoprotein can be trended over time to gauge response to treatment of cancers that produce the protein.",

keywords = "Alpha-fetoprotein, Endometrial carcinoma, Endometroid, Hepatoid, Uterine cancer, Yolk sac tumor",

author = "Cailin O'Connell and Sylvia Jang and Paloma Monroig-Bosque and Anne Alaniz",

note = "Funding Information: C.O. is a Burroughs Wellcome Fund Scholar supported by a Burroughs Wellcome Fund Physician Scientist Institutional Award to the Texas A\&M University Academy of Physician Scientists (Grant ID: 1020069). ",

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AU - Monroig-Bosque, Paloma

AU - Alaniz, Anne

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KW - Uterine cancer

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Cracking the case: The diagnosis and treatment of a complex high-grade endometrial carcinoma with hepatoid, endometrioid, serous features and somatically derived yolk sac tumor component in a 50 year old female

Abstract

Keywords

ASJC Scopus subject areas

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