Cotreatment With Clofazimine and Rapamycin Eliminates Drug-Resistant Tuberculosis by Inducing Polyfunctional Central Memory T-Cell Responses

Keyphrases

• Mycobacterium Tuberculosis (M. tb) 100%
• Co-treatment 100%
• Rapamycin 100%
• Multidrug-resistant Tuberculosis (MDR-TB) 100%
• Memory T Cell Response 100%
• Central Memory T Cells 100%
• Polyfunctional 100%
• Clofazimine 100%
• Drug Resistance 40%
• Mouse Model 20%
• Combined Treatment 20%
• Associated Genes 20%
• Antibiotics 20%
• Tuberculosis 20%
• Recurrent Disease 20%
• Treatment Efficacy 20%
• Central Cell 20%
• Memory T Cells 20%
• Causative Agents 20%
• Latency 20%
• Memory Response 20%
• Fast Rates 20%
• Extensively Drug-resistant 20%
• Human Macrophages 20%
• Immunomodulator 20%
• Multiple Drugs 20%
• Central Memory 20%
• New Antibiotics 20%
• Inducing Autophagy 20%
• Alternate Therapy 20%
• Co-therapy 20%
• MDR Strains 20%
• XDR Strains 20%
• Kv1.3 Potassium Channel 20%

Medicine and Dentistry

• T-Cell Response 100%
• Rapamycin 100%
• Drug Resistant Tuberculosis 100%
• Memory T Cell 100%
• Clofazimine 100%
• Antibiotics 50%
• Drug Resistance 50%
• Mycobacterium Tuberculosis 25%
• Macrophage 25%
• Combination Therapy 25%
• Recurrent Disease 25%
• Drug Induced Disease 25%
• Autophagy 25%
• Memory Cell 25%
• Immunomodulating Agent 25%
• Potassium Channel Kv1.3 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Rapamycin 100%
• Drug Resistant Tuberculosis 100%
• Clofazimine 100%
• Antibiotics 50%
• Drug Resistance 50%
• Mouse Model 25%
• Combination Therapy 25%
• Recurrent Disease 25%
• Mycobacterium Tuberculosis 25%
• Potassium Channel Kv1.3 25%
• Immunomodulating Agent 25%
• Drug Induced Disease 25%