Correlation of clinical outcomes with β-glucan levels in patients with invasive candidiasis

Charles R. Sims, Siraya Jaijakul, John Mohr, Jose Rodriguez, Malcolm Finkelman, Luis Ostrosky-Zeichner

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

The correlation of β-glucan (BG) levels with clinical outcomes in invasive candidiasis (IC) remains unknown. Patients with proven IC were followed prospectively from diagnosis to outcome with twice-weekly serum BG sampling. Correlation of BG with clinical outcome was assessed in each patient. BG levels tend to decrease in successfully treated patients and increase in treatment failures. BG levels may be useful as surrogates for outcome evaluation of IC.

Original languageEnglish (US)
Pages (from-to)2104-2106
Number of pages3
JournalJournal of Clinical Microbiology
Volume50
Issue number6
DOIs
StatePublished - Jun 2012

ASJC Scopus subject areas

  • Microbiology (medical)

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