TY - JOUR
T1 - Coronary Artery Calcium Score
T2 - the “Mammogram” of the Heart?
AU - Cainzos-Achirica, Miguel
AU - Di Carlo, Philip A.
AU - Handy, Catherine E.
AU - Quispe, Renato
AU - Roura, Gerard
AU - Pinto, Xavier
AU - Blumenthal, Roger S.
AU - Comin-Colet, Josep
AU - Corbella, Xavier
AU - Blaha, Michael J.
N1 - Funding Information:
Michael J. Blaha reports grants from NIH, FDA, AHA, and Aetna Foundation; grants and personal fees from Amgen Foundation; and personal fees from Novartis, Sanofi/Regeneron, MedImmune, and Akcea.
Funding Information:
Xavier Pinto reports grants from FIS-ISCIII and CIBER-ISCIII and personal fees from Amgen, Abbott, Sanofi, Lacer, Rubio, and Esteve.
Publisher Copyright:
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2018/9/1
Y1 - 2018/9/1
N2 - Purpose of Review: To discuss the classic analogy of “coronary artery calcium (CAC) as a mammogram of the heart”, by evaluating the conceptual strengths, weaknesses, opportunities, and threats of a potential cardiovascular disease (CVD) screening strategy using CAC in apparently healthy adults. Recent Findings: CAC is typically used for further CVD risk assessment. CAC is also currently being used as a screening test in specific subgroups of individuals, particularly in some Asian countries. Although this has yielded valuable insights on the determinants and pathophysiology of CVD, whether this approach results in improved clinical outcomes compared to other assessment and management approaches is currently unclear. Summary: Although CAC and mammograms share a number of characteristics, there are also important conceptual differences. The evidence supporting CAC, which is a robust CVD risk assessment tool, for CVD screening purposes is currently very limited, and further research is needed.
AB - Purpose of Review: To discuss the classic analogy of “coronary artery calcium (CAC) as a mammogram of the heart”, by evaluating the conceptual strengths, weaknesses, opportunities, and threats of a potential cardiovascular disease (CVD) screening strategy using CAC in apparently healthy adults. Recent Findings: CAC is typically used for further CVD risk assessment. CAC is also currently being used as a screening test in specific subgroups of individuals, particularly in some Asian countries. Although this has yielded valuable insights on the determinants and pathophysiology of CVD, whether this approach results in improved clinical outcomes compared to other assessment and management approaches is currently unclear. Summary: Although CAC and mammograms share a number of characteristics, there are also important conceptual differences. The evidence supporting CAC, which is a robust CVD risk assessment tool, for CVD screening purposes is currently very limited, and further research is needed.
KW - Atherosclerosis
KW - Cardiovascular disease
KW - Coronary artery calcium
KW - Mammogram
KW - Risk assessment
KW - Screening
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U2 - 10.1007/s11886-018-1020-9
DO - 10.1007/s11886-018-1020-9
M3 - Review article
C2 - 29987623
AN - SCOPUS:85049776003
VL - 20
JO - Current Cardiology Reports
JF - Current Cardiology Reports
SN - 1523-3782
IS - 9
M1 - 70
ER -