La malattia coronarica del cuore trapiantato: Interazione fisiopatologica tra sistema immunitario, infezioni e sindrome metabolica

Translated title of the contribution: Coronary allograft vasculopathy: Pathophysiological interaction between the immune system, infections and metabolic syndrome

Luciano Potena, Rossella Ferrara, Edward S. Mocarski, David B. Lewis, John P. Cooke, Francesco Grigioni, Fabio Coccolo, Gaia Magnani, Francesco Fallani, Carlo Magelli, Hannah A. Valantine, Angelo Branzi

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Cardiac allograft vasculopathy is still the main cause of long-term graft loss after heart transplantation. Indeed, recent advances in immunosuppression management led to a significant improvement in short-term survival, while long-term death rate did not change significantly in the last 20 years. In this paper, we will review the latest advances in the understanding of this peculiar form of atherosclerosis, focusing on the mechanisms that can be potentially targeted by specific therapeutic interventions.

Translated title of the contributionCoronary allograft vasculopathy: Pathophysiological interaction between the immune system, infections and metabolic syndrome
Original languageItalian
Pages (from-to)73-82
Number of pages10
JournalGiornale Italiano di Cardiologia
Volume8
Issue number2
StatePublished - Feb 1 2007

Keywords

  • Atherosclerosis
  • Cytomegalovirus
  • Endothelium
  • Heart transplantation
  • Metabolic syndrome
  • Rejection

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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