Corneal Involvement in Wallenberg Syndrome: Case Report and Literature Review

Francesco Pellegrini, Emanuela Interlandi, Alessandra Cuna, Erika Mandarà, Andrew G. Lee

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


A 47-year-old man with Wallenberg syndrome after a stroke in the territory of the left vertebrobasilar artery and posterior inferior cerebellar artery, presented a week later complaining of visual loss in the left eye. Examination showed corneal anaesthesia associated with a neurotrophic corneal epithelial defect. Corneal involvement secondary to trigeminal neuropathy in Wallenberg syndrome is not frequently reported and may lead to epithelial erosion and neurotrophic keratopathy. Clinicians should be aware that visual loss can occur from a neurogenic basis (e.g., Wallenberg syndrome) due to neurotrophic keratopathy. The use of cocaine, a potential cause of neurotrophic keratopathy, should also be suspected in the appropriate clinical scenario.

Original languageEnglish (US)
Pages (from-to)54-58
Number of pages5
Issue number1
StateE-pub ahead of print - Apr 8 2020


  • Wallenberg syndrome
  • neurotrophic keratitis
  • trigeminal nucleus

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology


Dive into the research topics of 'Corneal Involvement in Wallenberg Syndrome: Case Report and Literature Review'. Together they form a unique fingerprint.

Cite this