Coregistration of simulated aneurysms by finite element analysis for evaluation of growth

Gabriel Acevedo-Bolton, Brad Dispensa, David Saloner, Liang-Der Jou

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Understanding the growth patterns of cerebral aneurysms would aid us in determining the essential mechanical factors that may contribute to the initiation, growth, and rupture of these aneurysms and timing of the treatments. Determining the growth patterns of an aneurysm requires registration of a growing geometry; however, co-registration of growing aneurysms is often a great challenge because of deformation in the proximal and distal vasculatures. In this study, we design a simple experiment that allows us to simulate the process of aneurysm growth and to investigate several co-registration algorithms. The experiments involved introduction of a bulge to rubber latex tubing by injection of magnetic resonance contrast agent. Images of the rubber tubing were used to create geometric models for numerical simulations and analyses. Vessels away from the simulated aneurysm were aligned by numerical simulation. We find that vessel alignment gives a better estimation of geometric changes than co-registration of fiducial markers.

Original languageEnglish (US)
Title of host publicationProceedings of the 2005 Summer Bioengineering Conference, 2005 SBC
Number of pages2
StatePublished - Dec 1 2005
Event2005 Summer Bioengineering Conference - Vail, CO, United States
Duration: Jun 22 2005Jun 26 2005


Other2005 Summer Bioengineering Conference
Country/TerritoryUnited States
CityVail, CO

ASJC Scopus subject areas

  • Engineering(all)


Dive into the research topics of 'Coregistration of simulated aneurysms by finite element analysis for evaluation of growth'. Together they form a unique fingerprint.

Cite this