Contrast and accuracy of relaxation time measurements in acquired and synthesized multislice magnetic resonance images

S. Majumdar, H. D. Sostman, J. R. Macfall

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

The effects of interslice spacing, the number of data points and other factors on the accuracy of relaxation time measurements and contrast have been investigated for both acquired and synthesized multislice MR images using experiments and computer simulations. The cross-excitation between adjacent slices in multislice imaging affects both contrast and derived relaxation times. Such measurements also are affected by the T1 and T2 of the materials imaged, the pulse sequence timing parameters, and the number of data points used to estimate the relaxation times. Errors in T1 and T2 may be severe, particularly for slice spacings less than 0.5 slice thickness and for long T1 and T2 materials. Consequently, the difference in signal intensities between two materials with different relaxation times also varies with slice spacing and between acquired and synthetic images, particularly for strongly T1-weighted images.

Original languageEnglish (US)
Pages (from-to)119-127
Number of pages9
JournalInvestigative Radiology
Volume24
Issue number2
DOIs
StatePublished - Feb 1989

Keywords

  • Accuracy of T and T
  • Multislice MRI
  • Synthesized images

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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