Contrast agents

Ersan Altun; Diego R. Martin; Richard C. Semelka

doi:10.1002/9781119012979.ch19

Contrast agents

Ersan Altun, Diego R. Martin, Richard C. Semelka

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This chapter focuses on the categorization of magnetic resonance imaging (MRI) contrast agents, enhancement and pharmocokinetic properties of MRI contrast agents, toxicities and complications of administrations of MRI contrast agents, and practical guidelines for administration of MRI contrast agents. MRI contrast agents are classified into three main types: (1) Gadolinium-based contrast agents (GBCAs), (2) iron-based contrast agent, and (3) manganese-based contrast agents. GBCAs are overwhelmingly the most commonly used MRI contrast agents. They are essential for the detection and characterization of tumors, detection of inflammation and fibrosis, assessment of organ perfusion, and delineation of vessels and related vascular pathologies. GBCAs are generally considered to have no nephrotoxicity at approved dosages for MRI. Based on the stability of GBCAs and incidence of nephrogenic systemic fibrosis (NSF) associated with specific GBCAs, they were classified into three groups: high-risk, intermediate-risk, and low-risk agents.

Original language	English (US)
Title of host publication	Abdominal-Pelvic MRI
Subtitle of host publication	Fourth Edition
Publisher	Wiley
Pages	1425-1442
Number of pages	18
ISBN (Electronic)	9781119012979
ISBN (Print)	9781119012931
DOIs	https://doi.org/10.1002/9781119012979.ch19
State	Published - Jan 1 2015

ASJC Scopus subject areas

General Medicine

Access to Document

10.1002/9781119012979.ch19

Cite this

@inbook{1b7ff31cc669407cb2a0b09cd92ff3bf,

title = "Contrast agents",

abstract = "This chapter focuses on the categorization of magnetic resonance imaging (MRI) contrast agents, enhancement and pharmocokinetic properties of MRI contrast agents, toxicities and complications of administrations of MRI contrast agents, and practical guidelines for administration of MRI contrast agents. MRI contrast agents are classified into three main types: (1) Gadolinium-based contrast agents (GBCAs), (2) iron-based contrast agent, and (3) manganese-based contrast agents. GBCAs are overwhelmingly the most commonly used MRI contrast agents. They are essential for the detection and characterization of tumors, detection of inflammation and fibrosis, assessment of organ perfusion, and delineation of vessels and related vascular pathologies. GBCAs are generally considered to have no nephrotoxicity at approved dosages for MRI. Based on the stability of GBCAs and incidence of nephrogenic systemic fibrosis (NSF) associated with specific GBCAs, they were classified into three groups: high-risk, intermediate-risk, and low-risk agents.",

author = "Ersan Altun and Martin, {Diego R.} and Semelka, {Richard C.}",

note = "Publisher Copyright: {\textcopyright} 2016 by John Wiley & Sons Ltd.",

year = "2015",

month = jan,

day = "1",

doi = "10.1002/9781119012979.ch19",

language = "English (US)",

isbn = "9781119012931",

pages = "1425--1442",

booktitle = "Abdominal-Pelvic MRI",

publisher = "Wiley",

address = "United Kingdom",

}

TY - CHAP

T1 - Contrast agents

AU - Altun, Ersan

AU - Martin, Diego R.

AU - Semelka, Richard C.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - This chapter focuses on the categorization of magnetic resonance imaging (MRI) contrast agents, enhancement and pharmocokinetic properties of MRI contrast agents, toxicities and complications of administrations of MRI contrast agents, and practical guidelines for administration of MRI contrast agents. MRI contrast agents are classified into three main types: (1) Gadolinium-based contrast agents (GBCAs), (2) iron-based contrast agent, and (3) manganese-based contrast agents. GBCAs are overwhelmingly the most commonly used MRI contrast agents. They are essential for the detection and characterization of tumors, detection of inflammation and fibrosis, assessment of organ perfusion, and delineation of vessels and related vascular pathologies. GBCAs are generally considered to have no nephrotoxicity at approved dosages for MRI. Based on the stability of GBCAs and incidence of nephrogenic systemic fibrosis (NSF) associated with specific GBCAs, they were classified into three groups: high-risk, intermediate-risk, and low-risk agents.

AB - This chapter focuses on the categorization of magnetic resonance imaging (MRI) contrast agents, enhancement and pharmocokinetic properties of MRI contrast agents, toxicities and complications of administrations of MRI contrast agents, and practical guidelines for administration of MRI contrast agents. MRI contrast agents are classified into three main types: (1) Gadolinium-based contrast agents (GBCAs), (2) iron-based contrast agent, and (3) manganese-based contrast agents. GBCAs are overwhelmingly the most commonly used MRI contrast agents. They are essential for the detection and characterization of tumors, detection of inflammation and fibrosis, assessment of organ perfusion, and delineation of vessels and related vascular pathologies. GBCAs are generally considered to have no nephrotoxicity at approved dosages for MRI. Based on the stability of GBCAs and incidence of nephrogenic systemic fibrosis (NSF) associated with specific GBCAs, they were classified into three groups: high-risk, intermediate-risk, and low-risk agents.

UR - http://www.scopus.com/inward/record.url?scp=85218383374&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85218383374&partnerID=8YFLogxK

U2 - 10.1002/9781119012979.ch19

DO - 10.1002/9781119012979.ch19

M3 - Chapter

AN - SCOPUS:85218383374

SN - 9781119012931

SP - 1425

EP - 1442

BT - Abdominal-Pelvic MRI

PB - Wiley

ER -

Contrast agents

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this