Continuous Blood Pressure Measurement From Invasive to Unobtrusive: Celebration of 200th Birth Anniversary of Carl Ludwig

Xiao Rong Ding, Ni Zhao, Guang Zhong Yang, Roderic I. Pettigrew, Benny Lo, Fen Miao, Ye Li, Jing Liu, Yuan Ting Zhang

Research output: Contribution to journalArticle

61 Scopus citations

Abstract

The year 2016 marks the 200th birth anniversary of Carl Friedrich Wilhelm Ludwig (1816-1895). As one of the most remarkable scientists, Ludwig invented the kymograph, which for the first time enabled the recording of continuous blood pressure (BP), opening the door to the modern study of physiology. Almost a century later, intraarterial BP monitoring through an arterial line has been used clinically. Subsequently, arterial tonometry and volume clamp method were developed and applied in continuous BP measurement in a noninvasive way. In the last two decades, additional efforts have been made to transform the method of unobtrusive continuous BP monitoring without the use of a cuff. This review summarizes the key milestones in continuous BP measurement; that is, kymograph, intraarterial BP monitoring, arterial tonometry, volume clamp method, and cuffless BP technologies. Our emphasis is on recent studies of unobtrusive BP measurements as well as on challenges and future directions.

Original languageEnglish (US)
Article number7676313
Pages (from-to)1455-1465
Number of pages11
JournalIEEE Journal of Biomedical and Health Informatics
Volume20
Issue number6
DOIs
StatePublished - Nov 2016

Keywords

  • Carl ludwig
  • continuous
  • cuffless blood pressure (BP)
  • kymograph
  • unobtrusive

ASJC Scopus subject areas

  • Biotechnology
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Health Information Management

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