Contact angle changes induced by immunocomplex formation

Jong Hoon Kim; Amy Q. Shen; Kyong Hoon Lee; Gerard A. Cangelosi; Jae Hyun Chung

doi:10.1039/c3an02189k

Contact angle changes induced by immunocomplex formation

Jong Hoon Kim, Amy Q. Shen, Kyong Hoon Lee, Gerard A. Cangelosi, Jae Hyun Chung

Houston Methodist

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.

Original language	English (US)
Pages (from-to)	1340-1344
Number of pages	5
Journal	Analyst
Volume	139
Issue number	6
DOIs	https://doi.org/10.1039/c3an02189k
State	Published - Feb 17 2014

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Environmental Chemistry
Spectroscopy
Electrochemistry

Access to Document

10.1039/c3an02189k

Cite this

@article{a127187574a044e9a41c105ae608b852,

title = "Contact angle changes induced by immunocomplex formation",

abstract = "Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.",

author = "Kim, {Jong Hoon} and Shen, {Amy Q.} and Lee, {Kyong Hoon} and Cangelosi, {Gerard A.} and Chung, {Jae Hyun}",

year = "2014",

month = feb,

day = "17",

doi = "10.1039/c3an02189k",

language = "English (US)",

volume = "139",

pages = "1340--1344",

journal = "Analyst",

issn = "0003-2654",

publisher = "Royal Society of Chemistry",

number = "6",

}

TY - JOUR

T1 - Contact angle changes induced by immunocomplex formation

AU - Kim, Jong Hoon

AU - Shen, Amy Q.

AU - Lee, Kyong Hoon

AU - Cangelosi, Gerard A.

AU - Chung, Jae Hyun

PY - 2014/2/17

Y1 - 2014/2/17

N2 - Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.

AB - Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.

UR - http://www.scopus.com/inward/record.url?scp=84894268116&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84894268116&partnerID=8YFLogxK

U2 - 10.1039/c3an02189k

DO - 10.1039/c3an02189k

M3 - Article

C2 - 24482797

AN - SCOPUS:84894268116

SN - 0003-2654

VL - 139

SP - 1340

EP - 1344

JO - Analyst

JF - Analyst

IS - 6

ER -

Contact angle changes induced by immunocomplex formation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this