Contact angle changes induced by immunocomplex formation

Jong Hoon Kim, Amy Q. Shen, Kyong Hoon Lee, Gerard A. Cangelosi, Jae Hyun Chung

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Immunoassays analyzing interactions between antigens and antibodies can be affected by capillary action together with binding affinity. This paper studies contact-angle changes of bacterial suspensions on antibody immobilized surfaces. The capillary action and the dried pattern of the bacterial suspensions are analyzed and correlated with specific- and nonspecific bindings between bacteria and antibodies.

Original languageEnglish (US)
Pages (from-to)1340-1344
Number of pages5
JournalAnalyst
Volume139
Issue number6
DOIs
StatePublished - Feb 17 2014

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

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