TY - JOUR
T1 - Consensus conference on heart-kidney transplantation
AU - the Consensus Conference Participants
AU - Kobashigawa, Jon
AU - Dadhania, Darshana M.
AU - Farr, Maryjane
AU - Tang, W. H.Wilson
AU - Bhimaraj, Arvind
AU - Czer, Lawrence
AU - Hall, Shelley
AU - Haririan, Abdolreza
AU - Formica, Richard N.
AU - Patel, Jignesh
AU - Skorka, Rafael
AU - Fedson, Savitri
AU - Srinivas, Titte
AU - Testani, Jeffrey
AU - Yabu, Julie M.
AU - Cheng, Xingxing S.
AU - Adler, Eric
AU - Akalin, Enver
AU - Anderson, Allen
AU - Birdwell, Kelly
AU - Cohen, David
AU - Crew, R. John
AU - Eisen, Howard
AU - Feller, Erika
AU - Fischbach, Bernie
AU - Gallon, Lorenzo
AU - Gass, Alan
AU - Gonzalez, Juan
AU - Horn, Evelyn
AU - Inker, Lesley
AU - Johnson, Maryl
AU - Khush, Kiran
AU - Lefkowitz, Heather
AU - Moiz, Abdul
AU - Nathan, Sriram
AU - Nsair, Ali
AU - Peng, Alice
AU - Poggio, Emilio
AU - Radovancevic, Rajko
AU - Ravichandran, Ashwin
AU - Serur, David
AU - Zucker, Mark
N1 - Funding Information:
The authors of this manuscript have conflicts of interest to disclose as described by the . Dr. Kobashigawa has research grants from Novartis, Alexion, and CSL Behring. The other authors have no conflicts of interest to disclose. American Journal of Transplantation
Publisher Copyright:
© 2021 The American Society of Transplantation and the American Society of Transplant Surgeons
PY - 2021/7
Y1 - 2021/7
N2 - Simultaneous heart-kidney transplant (sHK) has enabled the successful transplantation of patients with end-stage heart disease and concomitant kidney disease, with non-inferior outcomes to heart transplant (HT) alone. The decision for sHK is challenged by difficulties in differentiating those patients with a significant component of reversible kidney injury due to cardiorenal syndrome who may recover kidney function after HT, from those with intrinsic advanced kidney disease who would benefit most from sHK. A consensus conference on sHK took place on June 1, 2019 in Boston, Massachusetts. The conference represented a collaborative effort by experts in cardiothoracic and kidney transplantation from centers across the United States to explore the development of guidelines for the interdisciplinary criteria for kidney transplantation in the sHK candidate, to evaluate the current allocation of kidneys to follow the heart for sHK, and to recommend standardized care for the management of sHK recipients. The conference served as a forum to unify criteria between the different specialties and to forge a pathway for patients who may need dual organ transplantation. Due to the continuing shortage of available donor organs, ethical problems related to multi-organ transplantation were also debated. The findings and consensus statements are presented.
AB - Simultaneous heart-kidney transplant (sHK) has enabled the successful transplantation of patients with end-stage heart disease and concomitant kidney disease, with non-inferior outcomes to heart transplant (HT) alone. The decision for sHK is challenged by difficulties in differentiating those patients with a significant component of reversible kidney injury due to cardiorenal syndrome who may recover kidney function after HT, from those with intrinsic advanced kidney disease who would benefit most from sHK. A consensus conference on sHK took place on June 1, 2019 in Boston, Massachusetts. The conference represented a collaborative effort by experts in cardiothoracic and kidney transplantation from centers across the United States to explore the development of guidelines for the interdisciplinary criteria for kidney transplantation in the sHK candidate, to evaluate the current allocation of kidneys to follow the heart for sHK, and to recommend standardized care for the management of sHK recipients. The conference served as a forum to unify criteria between the different specialties and to forge a pathway for patients who may need dual organ transplantation. Due to the continuing shortage of available donor organs, ethical problems related to multi-organ transplantation were also debated. The findings and consensus statements are presented.
KW - clinical research/practice
KW - ethics
KW - ethics and public policy
KW - heart disease
KW - heart transplantation/cardiology
KW - immunosuppressant
KW - kidney disease
KW - kidney transplantation/nephrology
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U2 - 10.1111/ajt.16512
DO - 10.1111/ajt.16512
M3 - Article
C2 - 33527725
AN - SCOPUS:85101141408
VL - 21
SP - 2459
EP - 2467
JO - American Journal of Transplantation
JF - American Journal of Transplantation
SN - 1600-6135
IS - 7
ER -