Congenital neuroblastoma in a neonate with isotretinoin embryopathy

Shiley Aguilar, Chrystal Louis, John Hicks, Peter Zage, Heidi Russell

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


We describe a neonate with isotretinoin embryopathy and an incidental finding of congenital neuroblastoma. Diffuse liver metastases led to the decision to provide oncologic therapy followed by tumor resection. Despite the possible need for chronic care related to the comorbidities of the isotretinoin embryopathy and oncologic management, the patient remains disease-free. Because of the uncertain etiology of neuroblastoma, it remains unclear whether exposure to isotretinoin during embryogenesis and fetal development had an oncogenic effect on this patient.

Original languageEnglish (US)
Pages (from-to)e75-e77
JournalJournal of pediatric hematology/oncology
Issue number2
StatePublished - Mar 2014


  • congenital
  • isotretinoin embryopathy
  • metastatic
  • neuroblastoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology


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