Confinement-induced entropic recoil of single DNA molecules in a nanofluidic structure

S. W.P. Turner; M. Cabodi; H. G. Craighead

Confinement-induced entropic recoil of single DNA molecules in a nanofluidic structure

S. W.P. Turner, M. Cabodi, H. G. Craighead

Research output: Contribution to journal › Article › peer-review

Abstract

The behavior of DNA molecules was studied in a nanofluidic device near the interface of two regions. An electric field was applied to drive the molecules. With removal of the electric field, the molecules recoil to the higher-entropy region with a profile characteristic of a force localized to the interface. Results showed that this is consistent with a confinement-mediated entropic force, distinct from the well-known entropic elasticity.

Original language	English (US)
Article number	128103
Pages (from-to)	1281031-1281034
Number of pages	4
Journal	Physical Review Letters
Volume	88
Issue number	12
State	Published - Mar 25 2002

ASJC Scopus subject areas

Physics and Astronomy(all)

Cite this

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abstract = "The behavior of DNA molecules was studied in a nanofluidic device near the interface of two regions. An electric field was applied to drive the molecules. With removal of the electric field, the molecules recoil to the higher-entropy region with a profile characteristic of a force localized to the interface. Results showed that this is consistent with a confinement-mediated entropic force, distinct from the well-known entropic elasticity.",

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AB - The behavior of DNA molecules was studied in a nanofluidic device near the interface of two regions. An electric field was applied to drive the molecules. With removal of the electric field, the molecules recoil to the higher-entropy region with a profile characteristic of a force localized to the interface. Results showed that this is consistent with a confinement-mediated entropic force, distinct from the well-known entropic elasticity.

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Confinement-induced entropic recoil of single DNA molecules in a nanofluidic structure

Abstract

ASJC Scopus subject areas

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