Confinement-induced entropic recoil of single DNA molecules in a nanofluidic structure

S. W.P. Turner, M. Cabodi, H. G. Craighead

Research output: Contribution to journalArticlepeer-review

248 Scopus citations


The behavior of DNA molecules was studied in a nanofluidic device near the interface of two regions. An electric field was applied to drive the molecules. With removal of the electric field, the molecules recoil to the higher-entropy region with a profile characteristic of a force localized to the interface. Results showed that this is consistent with a confinement-mediated entropic force, distinct from the well-known entropic elasticity.

Original languageEnglish (US)
Article number128103
Pages (from-to)1281031-1281034
Number of pages4
JournalPhysical Review Letters
Issue number12
StatePublished - Mar 25 2002

ASJC Scopus subject areas

  • Physics and Astronomy(all)


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