Concurrent primary peritoneal low-grade serous carcinoma and endometrial high-grade serous carcinoma

Megan G. Lockyer, Michael T. Deavers, Neda Zarrin-Khameh

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A 64-yr-old postmenopausal woman with high-grade squamous intraepithelial lesion and atypical glandular cell of undetermined significance on her Pap test was found to have endometrial serous carcinoma (high grade) involving a polyp in a subsequent endometrial biopsy. She underwent hysterectomy and bilateral salpingo-oophorectomy with multiple biopsies of the peritoneum. Microscopic examination of the entirely submitted uterus showed no residual serous carcinoma. Multiple foci of low-grade serous tumor with extensive calcifications and psammoma bodies were identified on the surfaces of the left fallopian tube, ovaries, and biopsies of the peritoneum, consistent with peritoneal primary low-grade serous carcinoma. To our knowledge, this is the first reported case of low-grade serous carcinoma of the peritoneum with a concurrent (high-grade) serous carcinoma of the endometrium arising from an endometrial polyp.

Original languageEnglish (US)
Pages (from-to)288-292
Number of pages5
JournalInternational Journal of Gynecological Pathology
Volume34
Issue number3
DOIs
StatePublished - Apr 22 2015

Keywords

  • Endometrial polyp
  • Low-grade serous carcinoma of peritoneum
  • Serous carcinoma of endometrium

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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