Concomitant Mitral Transcatheter Edge-to-Edge Repair and Transcatheter Closure of Perforated Anterior Mitral Valve Leaflet

Shriya K. Prakash; Caitlyn Andreas; Chloe Kharsa; Gal Sella; Catherine Teng; Kamran Sherwani; Wasiq F. Rawasia; Fernando Ramirez Del Val; Stephen H. Little; Sachin S. Goel

doi:10.1016/j.jaccas.2025.103749

Concomitant Mitral Transcatheter Edge-to-Edge Repair and Transcatheter Closure of Perforated Anterior Mitral Valve Leaflet

Shriya K. Prakash, Caitlyn Andreas, Chloe Kharsa, Gal Sella, Catherine Teng, Kamran Sherwani, Wasiq F. Rawasia, Fernando Ramirez Del Val, Stephen H. Little, Sachin S. Goel

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We present the case of a 76-year-old man with a previous history of surgical aortic valve replacement 3 years earlier for infective endocarditis, nonischemic cardiomyopathy, and severe secondary mitral regurgitation (SMR) who presented with worsening dyspnea on exertion. Echocardiography revealed severe SMR and a perforation at the base of the A1 scallop of the anterior mitral valve leaflet (AMVL). The patient was deemed at high surgical risk. After multidisciplinary team discussion, we proceeded with mitral transcatheter edge to edge repair with 2 MitraClips (Abbott) and concomitant transcatheter closure of the perforation of the AMVL with an Amplatzer Duct Occluder II (Abbott) device.

Original language	English (US)
Article number	103749
Journal	JACC: Case Reports
Volume	30
Issue number	9
DOIs	https://doi.org/10.1016/j.jaccas.2025.103749
State	Published - May 7 2025

Keywords

MitraClip
mitral transcatheter edge-to-edge repair (MTEER)
perforated mitral valve
plug
secondary mitral regurgitation

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1016/j.jaccas.2025.103749

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title = "Concomitant Mitral Transcatheter Edge-to-Edge Repair and Transcatheter Closure of Perforated Anterior Mitral Valve Leaflet",

abstract = "We present the case of a 76-year-old man with a previous history of surgical aortic valve replacement 3 years earlier for infective endocarditis, nonischemic cardiomyopathy, and severe secondary mitral regurgitation (SMR) who presented with worsening dyspnea on exertion. Echocardiography revealed severe SMR and a perforation at the base of the A1 scallop of the anterior mitral valve leaflet (AMVL). The patient was deemed at high surgical risk. After multidisciplinary team discussion, we proceeded with mitral transcatheter edge to edge repair with 2 MitraClips (Abbott) and concomitant transcatheter closure of the perforation of the AMVL with an Amplatzer Duct Occluder II (Abbott) device.",

keywords = "MitraClip, mitral transcatheter edge-to-edge repair (MTEER), perforated mitral valve, plug, secondary mitral regurgitation",

author = "Prakash, {Shriya K.} and Caitlyn Andreas and Chloe Kharsa and Gal Sella and Catherine Teng and Kamran Sherwani and Rawasia, {Wasiq F.} and {Del Val}, {Fernando Ramirez} and Little, {Stephen H.} and Goel, {Sachin S.}",

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doi = "10.1016/j.jaccas.2025.103749",

language = "English (US)",

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AU - Prakash, Shriya K.

AU - Andreas, Caitlyn

AU - Kharsa, Chloe

AU - Sella, Gal

AU - Teng, Catherine

AU - Sherwani, Kamran

AU - Rawasia, Wasiq F.

AU - Del Val, Fernando Ramirez

AU - Little, Stephen H.

AU - Goel, Sachin S.

PY - 2025/5/7

Y1 - 2025/5/7

N2 - We present the case of a 76-year-old man with a previous history of surgical aortic valve replacement 3 years earlier for infective endocarditis, nonischemic cardiomyopathy, and severe secondary mitral regurgitation (SMR) who presented with worsening dyspnea on exertion. Echocardiography revealed severe SMR and a perforation at the base of the A1 scallop of the anterior mitral valve leaflet (AMVL). The patient was deemed at high surgical risk. After multidisciplinary team discussion, we proceeded with mitral transcatheter edge to edge repair with 2 MitraClips (Abbott) and concomitant transcatheter closure of the perforation of the AMVL with an Amplatzer Duct Occluder II (Abbott) device.

AB - We present the case of a 76-year-old man with a previous history of surgical aortic valve replacement 3 years earlier for infective endocarditis, nonischemic cardiomyopathy, and severe secondary mitral regurgitation (SMR) who presented with worsening dyspnea on exertion. Echocardiography revealed severe SMR and a perforation at the base of the A1 scallop of the anterior mitral valve leaflet (AMVL). The patient was deemed at high surgical risk. After multidisciplinary team discussion, we proceeded with mitral transcatheter edge to edge repair with 2 MitraClips (Abbott) and concomitant transcatheter closure of the perforation of the AMVL with an Amplatzer Duct Occluder II (Abbott) device.

KW - MitraClip

KW - mitral transcatheter edge-to-edge repair (MTEER)

KW - perforated mitral valve

KW - plug

KW - secondary mitral regurgitation

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Concomitant Mitral Transcatheter Edge-to-Edge Repair and Transcatheter Closure of Perforated Anterior Mitral Valve Leaflet

Abstract

Keywords

ASJC Scopus subject areas

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