Computer-assisted predictions of signal peptidase processing sites

Rodney J. Folz, Jeffrey I. Gordon

Research output: Contribution to journalArticlepeer-review

48 Scopus citations


Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins, to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.

Original languageEnglish (US)
Pages (from-to)870-877
Number of pages8
JournalBiochemical and Biophysical Research Communications
Issue number2
StatePublished - Jul 31 1987

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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