Computer-assisted predictions of signal peptidase processing sites

Rodney J. Folz; Jeffrey I. Gordon

doi:10.1016/0006-291X(87)90611-5

Computer-assisted predictions of signal peptidase processing sites

Rodney J. Folz, Jeffrey I. Gordon

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins, to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.

Original language	English (US)
Pages (from-to)	870-877
Number of pages	8
Journal	Biochemical and Biophysical Research Communications
Volume	146
Issue number	2
DOIs	https://doi.org/10.1016/0006-291X(87)90611-5
State	Published - Jul 31 1987

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

Access to Document

10.1016/0006-291X(87)90611-5

Cite this

@article{1f522e32669d427a90e15b4b47486970,

title = "Computer-assisted predictions of signal peptidase processing sites",

abstract = "Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins, to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.",

author = "Folz, {Rodney J.} and Gordon, {Jeffrey I.}",

note = "Funding Information: This work was funded by NIH Grant HL-18577.",

year = "1987",

month = jul,

day = "31",

doi = "10.1016/0006-291X(87)90611-5",

language = "English (US)",

volume = "146",

pages = "870--877",

journal = "Biochemical and Biophysical Research Communications",

issn = "0006-291X",

publisher = "Academic Press",

number = "2",

}

TY - JOUR

T1 - Computer-assisted predictions of signal peptidase processing sites

AU - Folz, Rodney J.

AU - Gordon, Jeffrey I.

N1 - Funding Information: This work was funded by NIH Grant HL-18577.

PY - 1987/7/31

Y1 - 1987/7/31

N2 - Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins, to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.

AB - Computer programs are presented which incorporate 2 different algorithms for predicting the site of signal peptide cleavage for eukaryotic preproteins. These programs can be used to identify sites of signal peptidase cleavage of putative preproteins, to facilitate the design and interpretation of signal peptide mutagenesis experiments, and to engineer artificial prepolypeptides.

UR - http://www.scopus.com/inward/record.url?scp=0023669213&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023669213&partnerID=8YFLogxK

U2 - 10.1016/0006-291X(87)90611-5

DO - 10.1016/0006-291X(87)90611-5

M3 - Article

C2 - 3304288

AN - SCOPUS:0023669213

SN - 0006-291X

VL - 146

SP - 870

EP - 877

JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

IS - 2

ER -

Computer-assisted predictions of signal peptidase processing sites

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this