Computational Models in Biomedical Engineering: Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software

Miloš Kojić, Miljan Milošević, Arturas Ziemys

Research output: Book/ReportBook

1 Scopus citations

Abstract

Computational Models in Biomedical Engineering: Finite Element Models Based on Smeared Physical Fields: Theory, Solutions, and Software discusses novel computational methodologies developed by the authors that address a variety of topics in biomedicine, with concepts that rely on the so-called smeared physical field built into the finite element method. A new and straightforward methodology is represented by their Kojic Transport Model (KTM), where a composite smeared finite element (CSFE) as a FE formulation contains different fields (e.g., drug concentration, electrical potential) in a composite medium, such as tissue, which includes the capillary and lymphatic system, different cell groups and organelles. The continuum domains participate in the overall model according to their volumetric fractions. The governing laws and material parameters are assigned to each of the domains. Furthermore, the continuum fields are coupled at each FE node by connectivity elements which take into account biological barriers such as vessel walls and cells.

Original languageEnglish (US)
PublisherElsevier
Number of pages391
ISBN (Electronic)9780323884723
ISBN (Print)9780323906692
DOIs
StatePublished - Jan 1 2022

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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