Advances in computational techniques mitigated by faster computer hardware and improvements in software algorithms have increased interest in exploring their potential value for application in clinical research. Information derived from medical image data can be utilized to create computational models for simulating hemodynamics in cerebral aneurysms. In this chapter, we review the principles of computational fluid dynamics (CFD) aimed at this application and discuss results from selected studies which focused on developing CFD techniques for applications in clinical research. Validation studies comparing measurements with simulation results have demonstrated that this approach is viable and thereby encourage further development and refinement. They have also shown that multidisciplinary collaborative teams involving clinicians and clinical and basic scientists are needed to lead these exciting translational research efforts to fruition.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)