Compound K, a ginsenoside metabolite, inhibits colon cancer growth via multiple pathways including p53-p21 interactions

Keyphrases

• Colorectal Cancer 100%
• Colon Cancer 100%
• Cancer Growth 100%
• Multiple Pathways 100%
• Compound K 100%
• Ginsenoside Metabolites 100%
• HCT116 66%
• Protopanaxadiol 66%
• Tumor 33%
• Transcriptional Activation 33%
• Apoptosis 33%
• Western Blot Analysis 33%
• Cell Growth 33%
• Cyclin D1 (CCND1) 33%
• Multiple Tumors 33%
• Cell Apoptosis 33%
• Athymic nude Mice 33%
• Cancer Effects 33%
• In Vitro Assay 33%
• SW480 33%
• HT-29 33%
• Cyclin 33%
• HCT116 Cells 33%
• G1 Phase 33%
• Smad3 33%
• Active Compounds 33%
• Tumor-promoting 33%
• Colorectal Cancer Cells 33%
• Cyclin-dependent Kinase 4 (CDK4) 33%
• Intestinal Bacterial 33%
• Anticancer Effect 33%
• PCR Array 33%
• Cdc25 33%
• Xenograft Tumor Model 33%
• Forkhead Box O3 (FOXO3) 33%
• Ginseng 33%
• Antiproliferation 33%
• Cell Cycle Distribution 33%
• Saponins 33%
• Bacterial Metabolites 33%
• Nude Mouse Xenograft Model 33%
• Glucopyranosyl 33%
• Anti-colorectal Cancer 33%

Immunology and Microbiology

• P53 100%
• Colon 100%
• Metabolite 100%
• Colorectal Carcinoma 100%
• Cell Cycle 50%
• Programmed Cell Death 50%
• Xenograft 50%
• Nude Mouse 25%
• Real-Time Polymerase Chain Reaction 25%
• Downregulation 25%
• Western Blot 25%
• Cell Growth 25%
• Upregulation 25%
• Transactivation 25%
• Cycline 25%
• Transcription Initiation 25%
• Cyclin D1 25%
• Colorectal Cancer Cell Line 25%
• Cell Cycle G1 Phase 25%
• Ginseng 25%
• In Vitro 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Cancer Growth 100%
• Protein P53 100%
• Colorectal Carcinoma 100%
• Colon Carcinoma 100%
• Protopanaxadiol 40%
• Nude Mouse 20%
• Western Blot 20%
• Cycline 20%
• Tumor Model 20%
• Cyclin D1 20%
• Multiple Cancer 20%
• Ginseng 20%
• Saponin 20%