Complex haplotype structure of the human GNAS gene identifies a recombination hotspot centred on a single nucleotide polymorphism widely used in association studies

Keyphrases

• Single nucleotide Polymorphism 100%
• Recombination Hotspots 100%
• Association Study 100%
• Haplotype Structure 100%
• GNAS Gene 100%
• Genetic Markers 33%
• Exon 33%
• Complex Drug 33%
• Exon 5 33%
• Genetic Diversity 33%
• Genetic Variation 33%
• Cellular Response 33%
• Linkage Disequilibrium 33%
• G Protein 33%
• African American 33%
• Physiological Processes 33%
• Extracellular Signaling 33%
• Complex Disease 33%
• Disease Response 33%
• Exon 4 33%
• Primary Determinants 33%
• Allele Frequency 33%
• Drug Response 33%
• Single nucleotide Polymorphism Markers 33%
• Linkage Equilibrium 33%
• Linkage Disequilibrium Analysis 33%
• Haplotype Block 33%
• Haplotype Diversity 33%
• GNAS Locus 33%

Biochemistry, Genetics and Molecular Biology

• Single-Nucleotide Polymorphism 100%
• Haplotype 100%
• Exon 40%
• Gene Linkage Disequilibrium 40%
• Genomics 20%
• Intron 20%
• Genetic Divergence 20%
• Genetic Variation 20%
• Genetic Marker 20%
• Genetic Linkage 20%
• Physiological Process 20%
• Heterotrimeric G Protein 20%
• Drug Response 20%
• Gene Frequency 20%