Complement-mediated tumour growth: Implications for cancer nanotechnology and nanomedicines

S. M. Moghimi, T. L. Andresen

Research output: Contribution to journalLetter

21 Scopus citations

Abstract

The recent unexpected observation that complement activation helps tumour growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.

Original languageEnglish (US)
Pages (from-to)1571-1572
Number of pages2
JournalMolecular Immunology
Volume46
Issue number8-9
DOIs
StatePublished - May 2009

Keywords

  • C5a
  • Cancer
  • Complement system
  • Nanoparticles

ASJC Scopus subject areas

  • Molecular Biology
  • Immunology

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