Complement-mediated tumour growth: Implications for cancer nanotechnology and nanomedicines

S. M. Moghimi; T. L. Andresen

doi:10.1016/j.molimm.2009.02.014

Complement-mediated tumour growth: Implications for cancer nanotechnology and nanomedicines

S. M. Moghimi, T. L. Andresen

Research output: Contribution to journal › Letter › peer-review

23 Scopus citations

Abstract

The recent unexpected observation that complement activation helps tumour growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.

Original language	English (US)
Pages (from-to)	1571-1572
Number of pages	2
Journal	Molecular Immunology
Volume	46
Issue number	8-9
DOIs	https://doi.org/10.1016/j.molimm.2009.02.014
State	Published - May 2009

Keywords

C5a
Cancer
Complement system
Nanoparticles

ASJC Scopus subject areas

Molecular Biology
Immunology

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10.1016/j.molimm.2009.02.014

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title = "Complement-mediated tumour growth: Implications for cancer nanotechnology and nanomedicines",

abstract = "The recent unexpected observation that complement activation helps tumour growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.",

keywords = "C5a, Cancer, Complement system, Nanoparticles",

author = "Moghimi, {S. M.} and Andresen, {T. L.}",

note = "Funding Information: Financial support by the Danish Agency for Science, Technology and Innovation (Det Strategiske Forskningsr{\aa}d), reference 2106-08-0081, is gratefully acknowledged. Copyright: Copyright 2009 Elsevier B.V., All rights reserved.",

year = "2009",

month = may,

doi = "10.1016/j.molimm.2009.02.014",

language = "English (US)",

volume = "46",

pages = "1571--1572",

journal = "Molecular Immunology",

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T2 - Implications for cancer nanotechnology and nanomedicines

AU - Moghimi, S. M.

AU - Andresen, T. L.

N1 - Funding Information: Financial support by the Danish Agency for Science, Technology and Innovation (Det Strategiske Forskningsråd), reference 2106-08-0081, is gratefully acknowledged. Copyright: Copyright 2009 Elsevier B.V., All rights reserved.

PY - 2009/5

Y1 - 2009/5

N2 - The recent unexpected observation that complement activation helps tumour growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.

AB - The recent unexpected observation that complement activation helps tumour growth and progression has an important bearing on the future development of cancer nanomedicines for site-specific tumour targeting as these entities are capable of triggering complement. These issues are discussed and suggestions are provided for future design and development of safer and effective cancer nanomedicines.

KW - C5a

KW - Cancer

KW - Complement system

KW - Nanoparticles

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U2 - 10.1016/j.molimm.2009.02.014

DO - 10.1016/j.molimm.2009.02.014

M3 - Letter

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SN - 0161-5890

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JO - Molecular Immunology

JF - Molecular Immunology

IS - 8-9

ER -

Complement-mediated tumour growth: Implications for cancer nanotechnology and nanomedicines

Abstract

Keywords

ASJC Scopus subject areas

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