TY - JOUR
T1 - Comparative study of open and robot-assisted approaches to ureteropelvic junction obstruction in children ≤ 12 months
T2 - A multi-institutional retrospective analysis
AU - Abdulfattah, Suhaib
AU - Aghababian, Aznive
AU - Eftekharzadeh, Sahar
AU - Davis, Meghan
AU - Nadeem, Iqra
AU - Saxena, Sonam
AU - Kye, Nicole J.
AU - Weaver, John
AU - Bachtel, Hannah
AU - Nguyen, Catherine T.
AU - Khusid, Elizabeth
AU - Sze, Christina
AU - Zhang, Tenny
AU - Craig, Kiersten
AU - Xing, Monica
AU - Fischer, Katherine
AU - Godlewski, Karl
AU - De, Shuvro
AU - Arceo-Olaiz, Ricardo
AU - Long, Christopher
AU - Weiss, Dana
AU - Koh, Chester J.
AU - Akhavan, Ardavan
AU - Gundeti, Mohan
AU - Kirsch, Andrew J.
AU - Srinivasan, Arun K.
AU - Shukla, Aseem R.
AU - Mittal, Sameer
N1 - Publisher Copyright:
© 2025 Journal of Pediatric Urology Company.
PY - 2026/2
Y1 - 2026/2
N2 - Background The utilization of robot-assisted laparoscopic pyeloplasty (RALP) for the surgical correction of ureteropelvic junction obstruction (UPJO) continues to increase. The aim of this study was to determine whether robot-assisted laparoscopic pyeloplasty (RALP) is a safe and equally efficacious procedure compared to open pyeloplasty (OP) in infants ≤12 months old. Methods All patients ≤12 months old who underwent RALP or OP between January 2012 and January 2021 at five participating centers were included in this study. Patients who had pure laparoscopic approach, redo-pyeloplasty, ureterocalicostomy, abnormal nephro-ureteral anomalies, or lacked reviewable surgical records were excluded. Success was defined as lack of advanced endoscopic or re-do reconstructive intervention. Results 448 out of 497 patients met inclusion criteria: 151 RALP (34 %) and 297 OP (66 %). The median age at surgery was similar for both cohorts (p = 0.29). RALP compared to OP was associated with a higher usage of ureteral stent placement (100 % vs 88.9 %; p < 0.001) and longer procedure time (175 vs 160 min; p = 0.01), less administration of hospital morphine-equivalents post-operatively (p < 0.001) and similar length of stay (p = 0.96). There was no difference in the incidence of 30-day complications between the two groups, however higher-grade complications were seen in the OP group. Over a median follow of 26 months, the success rate after RALP and OP was 98.7 % and 89.6 % respectively (p < 0.001). Conclusion In this large, multi-institutional comparative series of infant pyeloplasty, our results demonstrate that RALP is not only safe and feasible, but also confers the advantages of reduced opioid usage, decreased risk of high-grade complications and decreased need for additional interventions during follow-up.
AB - Background The utilization of robot-assisted laparoscopic pyeloplasty (RALP) for the surgical correction of ureteropelvic junction obstruction (UPJO) continues to increase. The aim of this study was to determine whether robot-assisted laparoscopic pyeloplasty (RALP) is a safe and equally efficacious procedure compared to open pyeloplasty (OP) in infants ≤12 months old. Methods All patients ≤12 months old who underwent RALP or OP between January 2012 and January 2021 at five participating centers were included in this study. Patients who had pure laparoscopic approach, redo-pyeloplasty, ureterocalicostomy, abnormal nephro-ureteral anomalies, or lacked reviewable surgical records were excluded. Success was defined as lack of advanced endoscopic or re-do reconstructive intervention. Results 448 out of 497 patients met inclusion criteria: 151 RALP (34 %) and 297 OP (66 %). The median age at surgery was similar for both cohorts (p = 0.29). RALP compared to OP was associated with a higher usage of ureteral stent placement (100 % vs 88.9 %; p < 0.001) and longer procedure time (175 vs 160 min; p = 0.01), less administration of hospital morphine-equivalents post-operatively (p < 0.001) and similar length of stay (p = 0.96). There was no difference in the incidence of 30-day complications between the two groups, however higher-grade complications were seen in the OP group. Over a median follow of 26 months, the success rate after RALP and OP was 98.7 % and 89.6 % respectively (p < 0.001). Conclusion In this large, multi-institutional comparative series of infant pyeloplasty, our results demonstrate that RALP is not only safe and feasible, but also confers the advantages of reduced opioid usage, decreased risk of high-grade complications and decreased need for additional interventions during follow-up.
KW - Hydronephrosis
KW - Infants
KW - Minimally invasive surgery
KW - Pyeloplasty
KW - UPJO
KW - Ureteropelvic junction
UR - https://www.scopus.com/pages/publications/105014008096
UR - https://www.scopus.com/inward/citedby.url?scp=105014008096&partnerID=8YFLogxK
U2 - 10.1016/j.jpurol.2025.08.002
DO - 10.1016/j.jpurol.2025.08.002
M3 - Article
C2 - 40849240
AN - SCOPUS:105014008096
SN - 1477-5131
VL - 22
JO - Journal of Pediatric Urology
JF - Journal of Pediatric Urology
IS - 1
M1 - 105542
ER -