Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites

Junzhe Zhang; Yuhui Ma; Wenjiang Yang; Jingquan Xue; Yayun Ding; Changjian Xie; Wenhe Luo; Fuping Gao; Zhiyong Zhang; Yuliang Zhao; Zhifang Chai; Xiao He

doi:10.1039/C9NR00428A

Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites

Junzhe Zhang, Yuhui Ma, Wenjiang Yang, Jingquan Xue, Yayun Ding, Changjian Xie, Wenhe Luo, Fuping Gao, Zhiyong Zhang, Yuliang Zhao, Zhifang Chai, Xiao He

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This work highlights the superiority of the surface-radiolabeling strategy over the core-labeling strategy in the assembly of radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use in multimodal imaging and targeted therapy. It also implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization.

Original language	English (US)
Pages (from-to)	5909-5913
Number of pages	5
Journal	Nanoscale
Volume	11
Issue number	13
DOIs	https://doi.org/10.1039/C9NR00428A
State	Published - 2019

ASJC Scopus subject areas

Materials Science(all)

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10.1039/C9NR00428A

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Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites. / Zhang, Junzhe; Ma, Yuhui; Yang, Wenjiang; Xue, Jingquan; Ding, Yayun; Xie, Changjian; Luo, Wenhe; Gao, Fuping; Zhang, Zhiyong; Zhao, Yuliang; Chai, Zhifang; He, Xiao.

In: Nanoscale, Vol. 11, No. 13, 2019, p. 5909-5913.

Research output: Contribution to journal › Article › peer-review

Zhang, Junzhe ; Ma, Yuhui ; Yang, Wenjiang ; Xue, Jingquan ; Ding, Yayun ; Xie, Changjian ; Luo, Wenhe ; Gao, Fuping ; Zhang, Zhiyong ; Zhao, Yuliang ; Chai, Zhifang ; He, Xiao. / Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites. In: Nanoscale. 2019 ; Vol. 11, No. 13. pp. 5909-5913.

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abstract = "This work highlights the superiority of the surface-radiolabeling strategy over the core-labeling strategy in the assembly of radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use in multimodal imaging and targeted therapy. It also implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization.",

author = "Junzhe Zhang and Yuhui Ma and Wenjiang Yang and Jingquan Xue and Yayun Ding and Changjian Xie and Wenhe Luo and Fuping Gao and Zhiyong Zhang and Yuliang Zhao and Zhifang Chai and Xiao He",

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AU - Zhang, Junzhe

AU - Ma, Yuhui

AU - Yang, Wenjiang

AU - Xue, Jingquan

AU - Ding, Yayun

AU - Xie, Changjian

AU - Luo, Wenhe

AU - Gao, Fuping

AU - Zhang, Zhiyong

AU - Zhao, Yuliang

AU - Chai, Zhifang

AU - He, Xiao

PY - 2019

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N2 - This work highlights the superiority of the surface-radiolabeling strategy over the core-labeling strategy in the assembly of radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use in multimodal imaging and targeted therapy. It also implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization.

AB - This work highlights the superiority of the surface-radiolabeling strategy over the core-labeling strategy in the assembly of radioactive iron oxide nanoparticle (IONP)-based nanocomposites for use in multimodal imaging and targeted therapy. It also implies a possible overestimation of the labeling stability in previous studies and points out directions for further optimization.

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Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites

Abstract

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