Comparative Evaluation of Mitral Valve Strain by Deformation Tracking in 3D-Echocardiography

S. Ben Zekry, G. Lawrie, S. Little, W. Zoghbi, J. Freeman, A. Jajoo, S. Jain, J. He, A. Martynenko, R. Azencott

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


We present new algorithms to compute patient specific strain maps for mitral valve leaflets, by tracking and modeling deformations of the mitral valve apparatus in 3D echocardiography. We can then quantify comparisons of mitral leaflets strain maps between normal patients and cases of mitral valve prolapse or regurgitation. For patients with mitral valve regurgitation, we compare mitral leaflets strain maps between pre-surgery and post-surgery, to quantify the strain reduction due to mitral valve repair surgery.

Original languageEnglish (US)
Pages (from-to)402-412
Number of pages11
JournalCardiovascular Engineering and Technology
Issue number4
StatePublished - Dec 2012


  • 3D-echocardiography
  • Deformable shapes
  • Diffeomorphic tracking
  • Human mitral valve
  • Leaflet tissue strain

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine


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