@article{378c98a23ca74be5a596478337ff3084,
title = "Combined histiologic and molecular features reveal previously unappreciated subsets of lymphoma in AKXD recombinant inbred mice",
abstract = "Hematopoietic neoplasms developing in AKXD recombinant inbred, NFS.V+ and ICSBP knockout mice were assessed using morphologic, cytologic and molecular criteria that relate these disorders to human lymphoma and leukemia. Lymphoma types included precursor T-cell and B-cell lymphoblastic, small lymphocytic, splenic marginal zone, follicular, and diffuse large cell (DLCL). In addition to previously defined subtypes of DLCL composed of centroblasts or immunoblasts, two additional subtypes are defined here: lymphoblastic lymphoma like (LL) and lymphoma characterized by a histiocytic reaction (HS). DLCL(HS) were distinguished from true histiocytic lymphomas by the presence of clonal Ig gene rearrangements.",
keywords = "Diffuse large cell lymphoma, Mouse B-cell lymphoma, Oncogene, Proviral insertional mutagenesis, Splenic marginal zone lymphoma",
author = "Morse, {Herbert C.} and Qi, {Chen Feng} and Chattopadhyay, {Sisir K.} and Mitsuo Hori and Lekidelu Taddesse-Heath and Keiko Ozato and Hartley, {Janet W.} and Taylor, {Benjamin A.} and Ward, {Jerrold M.} and Jenkins, {Nancy A.} and Copeland, {Neal G.} and Fredrickson, {Torgny N.}",
note = "Funding Information: This work was supported in part by NCI grant CA33093 to BAT. We thank B. Rae Marshall for excellent editorial assistance and M. Firestone for careful and thoughtful efforts in organizing and sorting the data. The insights into related human pathologies provided by Dr E.S. Jaffe were invaluable. H.C. Morse III provided the concept, design, drafting of the article, critical revision as well as giving final approval. In addition he provide logistic support and data collection. C.-F. Qi and S.K. Chattopadhyay collected the data, provided technical support, study materials and helped to analyze and interpret the data. M. Hori collected the data, gave technical support and provided data interpretation. L. Taddesse-Heath provided study materials, collected and analyzed the data. K. Ozato provided study materials and assembled the data. J.W. Hartley collected and provided study materials, analyzed the data and helped with the revision of the manuscript. B.A. Taylor provided and assembled the data. J.M. Ward helped with data assembly, analysis of data and provided critical revision of the article. N.A. Jenkins and N.G. Copeland provided study materials, collected the data and gave final approval. T.N. Fredrickson contributed to the design, concept, data analysis and assembly of data, gave critical revision to the manuscript and provided final approval of the article.",
year = "2001",
doi = "10.1016/S0145-2126(01)00022-4",
language = "English (US)",
volume = "25",
pages = "719--733",
journal = "Leukemia Research",
issn = "0145-2126",
publisher = "Elsevier Ltd",
number = "8",
}