Renal dysfunction, a prevalent comorbidity in advanced heart failure, is associated with significant morbidity and mortality after heart transplantation. In the recent era, the field of combined heart-kidney transplantation has experienced great success in the treatment of both renal and cardiac dysfunction in end-stage disease states, and the number of transplants has increased dramatically. In this review, we discuss appropriate indications and selection criteria, overall and organ-specific outcomes, and future perspectives in the field of combined heart-kidney transplantation.

Original languageEnglish (US)
Pages (from-to)11-18
Number of pages8
JournalMethodist DeBakey cardiovascular journal
Issue number4
StatePublished - 2022


  • chronic kidney disease
  • deceased donor kidney transplantation
  • heart-kidney transplantation
  • orthotopic heart transplantation
  • transplant
  • Kidney Transplantation/adverse effects
  • Heart Transplantation/adverse effects
  • Humans
  • Heart Failure/complications
  • Treatment Outcome
  • Patient Selection

ASJC Scopus subject areas

  • Medicine(all)


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