Combined effects of ticarcillin and cefazolin on blood coagulation and platelet function

E. A. Natelson, W. T. Siebert, T. W. Williams, M. W. Bradshaw

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Combined intravenous infusions of ticarcillin and cefazolin given to normal volunteers resulted in a functional platelet defect which appeared to be determined primarily by the dose and duration of treatment with the penicillin component. No effect on soluble blood coagulation factors was evident. Acute administration of corticosteroids did not influence the prolonged bleeding times induced by extended ticarcillin infusions.

Original languageEnglish (US)
Pages (from-to)217-221
Number of pages5
JournalAmerican Journal of the Medical Sciences
Volume278
Issue number3
DOIs
StatePublished - 1979

ASJC Scopus subject areas

  • Medicine(all)

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