Co-production of nattokinase and poly (γ-glutamic acid) under solid-state fermentation using soybean and rice husk

Guangjun Nie, Zhubin Zhu, Fang Liu, Zhijie Nie, Yuchao Ye, Wenjin Yue

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The aim of this work was to study the co-production of nattokinase and poly (γ-glutamic acid) by Bacillus subtilis natto with soybean and rice husk under solid-state fermentation (SSF). The results showed that the size of soybean particle and rice husk significantly improved the co-production of nattokinase and poly (γ-glutamic acid), yielding 2503.4 IU/gs and 320 mg/gs, respectively in the improved culture medium composed of 16.7% soybean flour and 13.3% rice husk with 70% water content. The yields increased by approximate 7- and 2-fold factor relative to their original ones. Thus, the co-production of nattokinase and poly (γ-glutamic acid) under SSF could be considered as an efficient method to exploit agro-residues for economical production of some higher-value products.

Original languageEnglish (US)
Pages (from-to)718-724
Number of pages7
JournalBrazilian Archives of Biology and Technology
Volume58
Issue number5
DOIs
StatePublished - 2015

Keywords

  • Co-production
  • Nattokinase
  • Poly (γ-glutamic acid)
  • Rice husk
  • Solid-state fermentation

ASJC Scopus subject areas

  • General

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