Clostridium perfringens septicemia: A rare presentation and review of the literature

Clostridium perfringens is commonly found in the surrounding environment and is isolated from the intestinal tract of humans. It can become pathogenic with extremes of clinical presentation. We present a case of severe sepsis syndrome secondary to C perfringens with an unusual presentation of coexisting bilious pleural effusion. Despite an aggressive attempt at resuscitation and treatment, the patient died. C perfringens sepsis can cause severe sepsis syndrome with massive hemolysis and has an extremely high mortality. Bilious pleural effusions are rare complications of biliary tract disorders. We present a rare case of biliary pleural effusion in a patient with C perfringens sepsis.