Clostridium perfringens septicemia: A rare presentation and review of the literature

Mastian Chand, Ellen Gutkin, Sang H. Kim, Carl Urban, Melvin C. Hochman

Research output: Contribution to journalReview articlepeer-review


Clostridium perfringens is commonly found in the surrounding environment and is isolated from the intestinal tract of humans. It can become pathogenic with extremes of clinical presentation. We present a case of severe sepsis syndrome secondary to C perfringens with an unusual presentation of coexisting bilious pleural effusion. Despite an aggressive attempt at resuscitation and treatment, the patient died. C perfringens sepsis can cause severe sepsis syndrome with massive hemolysis and has an extremely high mortality. Bilious pleural effusions are rare complications of biliary tract disorders. We present a rare case of biliary pleural effusion in a patient with C perfringens sepsis.

Original languageEnglish (US)
Pages (from-to)115-118
Number of pages4
JournalInfectious Diseases in Clinical Practice
Issue number2
StatePublished - Mar 2012


  • Clostridium perfringens
  • bilious pleural effusion
  • hepatic gangrene
  • intravascular hemolysis
  • sepsis syndrome

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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