TY - JOUR
T1 - Clopidogrel use as a risk factor for poor outcomes after kidney transplantation
AU - Williams, Jennifer M.
AU - Tuttle-Newhall, Janet E.
AU - Schnitzler, Mark
AU - Dzebisashvili, Nino
AU - Xiao, Huiling
AU - Axelrod, David
AU - Mogal, Harveshp
AU - Lentine, Krista L.
N1 - Publisher Copyright:
© 2014 Elsevier Inc.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - BackgroundMethods:Results: Clopidogrel fills within 90 days of transplant were associated with 61% of increased relative mortality risk and 23% of increased graft failure risk. Risks were higher in those whose last clopidogrel fill was more than 90 days before transplantation (111% for death, 59% for graft loss).Conclusions: Clopidogrel use before kidney transplantation portends increased risks of post-transplant death and graft loss. Pharmacy claims may identify novel prognostic markers not currently captured in the transplant registry.
AB - BackgroundMethods:Results: Clopidogrel fills within 90 days of transplant were associated with 61% of increased relative mortality risk and 23% of increased graft failure risk. Risks were higher in those whose last clopidogrel fill was more than 90 days before transplantation (111% for death, 59% for graft loss).Conclusions: Clopidogrel use before kidney transplantation portends increased risks of post-transplant death and graft loss. Pharmacy claims may identify novel prognostic markers not currently captured in the transplant registry.
KW - Clopidogrel Death Graft loss Kidney transplantation Outcomes Pharmacy records
UR - http://www.scopus.com/inward/record.url?scp=84908126549&partnerID=8YFLogxK
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U2 - 10.1016/j.amjsurg.2014.06.007
DO - 10.1016/j.amjsurg.2014.06.007
M3 - Article
C2 - 25241952
AN - SCOPUS:84908126549
SN - 0002-9610
VL - 208
SP - 556
EP - 562
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 4
ER -