Clinically Meaningful Magnetic Resonance Endpoints Sensitive to Preataxic Spinocerebellar Ataxia Types 1 and 3

Keyphrases

• Clinically Significant 100%
• Magnetic Resonance 100%
• Spinocerebellar Ataxia 100%
• Spinocerebellar Ataxia Type 3 (SCA3) 100%
• Ataxia 30%
• Neurochemicals 30%
• Microstructural 20%
• Multisite Trials 20%
• Clinical Trials 10%
• Early Change 10%
• Brainstem 10%
• Area under the Curve 10%
• Activities of Daily Living 10%
• Imaging Protocol 10%
• Area under the Receiver Operating Characteristic Curve 10%
• Disease Diagnosis 10%
• Atrophy 10%
• Pons 10%
• Afferent Pathways 10%
• Multiple Comparisons 10%
• Magnetic Resonance Spectroscopy 10%
• Disease Effects 10%
• Mutation Carriers 10%
• Ataxic 10%
• Multiparametric MRI (mpMRI) 10%
• Magnetic Resonance Scan 10%
• Receiver Operating Characteristic Analysis 10%
• Early Symptoms 10%
• Cerebellar Peduncles 10%
• Efferent Pathways 10%
• Nonparametric Testing 10%
• Microstructural Damage 10%
• Diffusion MR Imaging 10%
• Cerebellar Afferents 10%
• Structural Diffusion 10%

Neuroscience

• Spinocerebellar Ataxia 100%
• Ataxia 50%
• Magnetic Resonance Imaging 16%
• Brainstem 16%
• Nuclear Magnetic Resonance Spectroscopy 16%
• Magnetic Resonance Imaging 16%
• Pons 16%
• Artificial Neural Network 16%
• Efferent Pathway 16%
• Afferent Pathway 16%