TY - JOUR
T1 - Clinical presentation of ductal carcinoma in situ of breast with intraluminal crystalloids
T2 - Radiologic-histologic correlation
AU - Jung, Minjung
AU - Maldonado, Joyce
AU - Schwartz, Mary R.
AU - Sneige, Nour
AU - Ayala, Alberto G.
AU - Ro, Jae Y.
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/12
Y1 - 2018/12
N2 - Intraluminal crystalloids have rarely been described in the breast, particularly in cases with ductal carcinoma in situ (DCIS). We recently encountered a case of DCIS of the breast associated with numerous intraluminal crystalloids. The patient presented with a mass in the right breast, and microcalcifications were detected on screening and diagnostic mammograms; the patient underwent needle biopsies, lumpectomy, and skin-sparing mastectomy. Invasive ductal carcinoma associated with extensive DCIS was diagnosed. Multiple refractile, eosinophilic crystalloids, with variable morphologies including rectangular, triangular and needle-like with sharp borders, were observed within the lumina of DCIS, besides calcium phosphate microcalcifications. We report this case together with a literature review on crystalloid-containing lesions in breast and non-breast tissues. We also studied radiologic findings of these crystalloids using a specimen radiograph.
AB - Intraluminal crystalloids have rarely been described in the breast, particularly in cases with ductal carcinoma in situ (DCIS). We recently encountered a case of DCIS of the breast associated with numerous intraluminal crystalloids. The patient presented with a mass in the right breast, and microcalcifications were detected on screening and diagnostic mammograms; the patient underwent needle biopsies, lumpectomy, and skin-sparing mastectomy. Invasive ductal carcinoma associated with extensive DCIS was diagnosed. Multiple refractile, eosinophilic crystalloids, with variable morphologies including rectangular, triangular and needle-like with sharp borders, were observed within the lumina of DCIS, besides calcium phosphate microcalcifications. We report this case together with a literature review on crystalloid-containing lesions in breast and non-breast tissues. We also studied radiologic findings of these crystalloids using a specimen radiograph.
KW - Ductal carcinoma in situ
KW - Intraluminal crystalloids
KW - Literature review
KW - Radiologic finding
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U2 - 10.1016/j.anndiagpath.2018.09.001
DO - 10.1016/j.anndiagpath.2018.09.001
M3 - Article
C2 - 30241034
AN - SCOPUS:85053447053
SN - 1092-9134
VL - 37
SP - 42
EP - 46
JO - Annals of Diagnostic Pathology
JF - Annals of Diagnostic Pathology
ER -