Clinical presentation of ductal carcinoma in situ of breast with intraluminal crystalloids: Radiologic-histologic correlation

Minjung Jung, Joyce Maldonado, Mary R. Schwartz, Nour Sneige, Alberto Ayala, Jae Ro

Research output: Contribution to journalArticle

Abstract

Intraluminal crystalloids have rarely been described in the breast, particularly in cases with ductal carcinoma in situ (DCIS). We recently encountered a case of DCIS of the breast associated with numerous intraluminal crystalloids. The patient presented with a mass in the right breast, and microcalcifications were detected on screening and diagnostic mammograms; the patient underwent needle biopsies, lumpectomy, and skin-sparing mastectomy. Invasive ductal carcinoma associated with extensive DCIS was diagnosed. Multiple refractile, eosinophilic crystalloids, with variable morphologies including rectangular, triangular and needle-like with sharp borders, were observed within the lumina of DCIS, besides calcium phosphate microcalcifications. We report this case together with a literature review on crystalloid-containing lesions in breast and non-breast tissues. We also studied radiologic findings of these crystalloids using a specimen radiograph.

Original languageEnglish (US)
Pages (from-to)42-46
Number of pages5
JournalAnnals of Diagnostic Pathology
Volume37
DOIs
StatePublished - Dec 1 2018

Keywords

  • Ductal carcinoma in situ
  • Intraluminal crystalloids
  • Literature review
  • Radiologic finding

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'Clinical presentation of ductal carcinoma in situ of breast with intraluminal crystalloids: Radiologic-histologic correlation'. Together they form a unique fingerprint.

Cite this