Clinical impact of transesophageal echocardiography in the diagnosis and management of infective endocarditis

Richard W. Lowry, William A. Zoghbi, William B. Baker, Richard A. Wray, Miguel A. Quiñones

Research output: Contribution to journalArticle

80 Scopus citations

Abstract

Transesophageal echocardiography (TEE) has assumed a prominent role in the diagnosis and management of infective endocarditis (IE). The impact of negative TEE findings on the management of patients suspected of having IE is not clear. To better understand how a negative TEE examination would influence patient management, the medical records of 93 consecutive patients undergoing TEE to evaluate for IE were ex amined. The influence of TEE was assessed based on changes in diagnosis, antibiotic therapy, or the need for surgical intervention during hospitalization. The negative predictive value of TEE was found to be 100% in native valves and 90% in prosthetic valves. The overall impact of negative TEE findings was significant in terms of final diagnosis and duration of antibiotic therapy (a negative TEE resulted in 60% reduction in antibiotic duration, p = 0.0001). These findings sug gest that in patients with native heart valves, a negative TEE examination virtually excludes IE. In patients with prosthetic valves, a negative TEE significantly decreases the likelihood of IE but does not completely exclude the diagnosis; therefore, in this setting, a negative finding should be closely correlated with the clinical course.

Original languageEnglish (US)
Pages (from-to)1089-1091
Number of pages3
JournalThe American Journal of Cardiology
Volume73
Issue number15
DOIs
StatePublished - Jun 1 1994

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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