Clinical functional genomics

Seren Carpenter, R. Steven Conlan

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations


Functional genomics is the study of how the genome and its products, including RNA and proteins, function and interact to affect different biological processes. The field of functional genomics includes transcriptomics, proteomics, metabolomics and epigenomics, as these all relate to controlling the genome leading to expression of particular phenotypes. By studying whole genomes— clinical genomics, transcriptomes and epigenomes—functional genomics allows the exploration of the diverse relationship between genotype and phenotype, not only for humans as a species but also in individuals, allowing an understanding and evaluation of how the functional genome ‘contributes’ to different diseases. Functional variation in disease can help us better understand that disease, although it is currently limited in terms of ethnic diversity, and will ultimately give way to more personalized treatment plans.

Original languageEnglish (US)
Article number4627
Issue number18
StatePublished - Sep 2021


  • Clinical adoption
  • Ethnic diversity
  • Functional genomics
  • Single cell analysis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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