Clindamycin-Resistant Group B Streptococcus and Failure of Intrapartum Prophylaxis to Prevent Early-Onset Disease

Anne J. Blaschke; Laurie S. Pulver; E. Kent Korgenski; Lucy A. Savitz; Judy A. Daly; Carrie L. Byington

doi:10.1016/j.jpeds.2009.10.048

Clindamycin-Resistant Group B Streptococcus and Failure of Intrapartum Prophylaxis to Prevent Early-Onset Disease

Anne J. Blaschke, Laurie S. Pulver, E. Kent Korgenski, Lucy A. Savitz, Judy A. Daly, Carrie L. Byington

Academic Institute

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.

Original language	English (US)
Pages (from-to)	501-503
Number of pages	3
Journal	Journal of Pediatrics
Volume	156
Issue number	3
DOIs	https://doi.org/10.1016/j.jpeds.2009.10.048
State	Published - Mar 2010

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1016/j.jpeds.2009.10.048

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title = "Clindamycin-Resistant Group B Streptococcus and Failure of Intrapartum Prophylaxis to Prevent Early-Onset Disease",

abstract = "Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.",

author = "Blaschke, \{Anne J.\} and Pulver, \{Laurie S.\} and Korgenski, \{E. Kent\} and Savitz, \{Lucy A.\} and Daly, \{Judy A.\} and Byington, \{Carrie L.\}",

note = "Funding Information: A.J.B. was supported by an NIH/NICHD Child Health Research Career Development Award ( 5K12HD001410-04 and 1K23AI079401-01A1 ), L.S.P. by the Primary Children's Medical Center Foundation , and C.L.B. by NIH/NICHD ( K-24 HD047249-01 ). The authors declare no conflicts of interest. ",

year = "2010",

month = mar,

doi = "10.1016/j.jpeds.2009.10.048",

language = "English (US)",

volume = "156",

pages = "501--503",

journal = "Journal of Pediatrics",

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T1 - Clindamycin-Resistant Group B Streptococcus and Failure of Intrapartum Prophylaxis to Prevent Early-Onset Disease

AU - Blaschke, Anne J.

AU - Pulver, Laurie S.

AU - Korgenski, E. Kent

AU - Savitz, Lucy A.

AU - Daly, Judy A.

AU - Byington, Carrie L.

N1 - Funding Information: A.J.B. was supported by an NIH/NICHD Child Health Research Career Development Award ( 5K12HD001410-04 and 1K23AI079401-01A1 ), L.S.P. by the Primary Children's Medical Center Foundation , and C.L.B. by NIH/NICHD ( K-24 HD047249-01 ). The authors declare no conflicts of interest.

PY - 2010/3

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N2 - Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.

AB - Guidelines recommend intrapartum antibiotic prophylaxis (IAP) for parturient women who have a screen positive for group B Streptococcus (GBS). Clindamycin should be used for IAP only if the maternal GBS isolate is susceptible. We report a case of clindamycin-resistant GBS disease in a newborn infant whose mother received clindamycin IAP, and we review clindamycin susceptibility testing.

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Clindamycin-Resistant Group B Streptococcus and Failure of Intrapartum Prophylaxis to Prevent Early-Onset Disease

Abstract

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