Chylous ascites, intestinal lymphangiectasia and the 'yellow-nail' syndrome

P. Mduhra, E. M.M. Quigley, M. N. Marsh

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


In 1964 Samman and White described 13 patients with lymphoedema of the lower extremities associated with an unusual dystrophy of the finger and toe nails: this they termed the 'yellow-nail' syndrome. Affected nails were thickened, excessively curved along both axes, very slow growing and of yellowish-grey hue; cuticle and lunula were usually absent and onycholysis was frequently evident1. Lower limb lymphangiography in most individuals revealed hypoplasia, or aplasia of the lymphatics,1-3 similar to that occurring in primary lymphoedema:4 other patients also developed pleural effusions of high protein content 5-7 or ascites3 8 suggestive of a more generalised disorder of the lymphatic system. Here we describe a patient in whom the classical 'yellow-nail' syndrome was associated with intestinal and chylous ascites.

Original languageEnglish (US)
Pages (from-to)1266-1269
Number of pages4
Issue number11
StatePublished - 1985

ASJC Scopus subject areas

  • Gastroenterology


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