Chylous ascites, intestinal lymphangiectasia and the 'yellow-nail' syndrome

P. Mduhra, E. M.M. Quigley, M. N. Marsh

Research output: Contribution to journalArticle

29 Scopus citations


In 1964 Samman and White described 13 patients with lymphoedema of the lower extremities associated with an unusual dystrophy of the finger and toe nails: this they termed the 'yellow-nail' syndrome. Affected nails were thickened, excessively curved along both axes, very slow growing and of yellowish-grey hue; cuticle and lunula were usually absent and onycholysis was frequently evident1. Lower limb lymphangiography in most individuals revealed hypoplasia, or aplasia of the lymphatics,1-3 similar to that occurring in primary lymphoedema:4 other patients also developed pleural effusions of high protein content 5-7 or ascites3 8 suggestive of a more generalised disorder of the lymphatic system. Here we describe a patient in whom the classical 'yellow-nail' syndrome was associated with intestinal and chylous ascites.

Original languageEnglish (US)
Pages (from-to)1266-1269
Number of pages4
Issue number11
StatePublished - 1985

ASJC Scopus subject areas

  • Gastroenterology

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