Chronic venous disorders of the leg: Epidemiology, outcomes, diagnosis and management

X. Kurz, S. R. Kahn, L. Abenhaim, D. Clement, L. Norgren, U. Baccaglini, A. Berard, J. P. Cooke, A. Cornu-Thenard, M. Depairon, J. A. Dormandy, I. Durand-Zaleski, G. R. Fowkes, D. L. Lamping, H. Partsch, J. H. Scurr, F. Zuccarelli

Research output: Contribution to journalArticlepeer-review

233 Scopus citations


Background. To critically review the classification, epidemiology outcomes, diagnosis and treatment of chronic venous disorders of the leg (CVDL), to issue evidence-based recommendations, and to identify areas requiring further research. Methods. Articles identified by an extensive literature search were scored by members of an international task force. Only those articles with a moderate or strong rating for internal validity were retained. Results. A scoring system weighing CVDL severity according to the probability of ulcer occurrence is proposed. Epidemiological data on the frequency of CVDL and its risk factors are reviewed. The following items are evaluated: costs associated with treatment; clinical outcomes related to CVDL and its treatment; available generic and disease-specific measures of quality of life; diagnostic procedures used to detect venous reflux; and efficacy of available treatments. Conclusions. CVDL is an important public health problem, based on its prevalence, cost and impact on quality of life. High-priority areas for research on CVDL are identified.

Original languageEnglish (US)
Pages (from-to)83-102
Number of pages20
JournalInternational Angiology
Issue number2
StatePublished - 1999


  • Diagnosis
  • Economics
  • Epidemiology
  • Outcome assessment
  • Quality of life
  • Therapeutics
  • Varicose vein
  • Varicose veins
  • Venous insufficiency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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