Chronic constipation in adults: Contemporary perspectives and clinical challenges. 2: Conservative, behavioural, medical and surgical treatment

Maura Corsetti, Steven Brown, Giuseppe Chiarioni, Eirini Dimidi, Thomas Dudding, Anton Emmanuel, Mark Fox, Alexander C. Ford, Pasquale Giordano, Ugo Grossi, Michelle Henderson, Charles H. Knowles, P. Ronan O’Connell, Eamonn M.M. Quigley, Magnus Simren, Robin Spiller, Kevin Whelan, William E. Whitehead, Andrew B. Williams, S. Mark Scott

Research output: Contribution to journalReview article

Abstract

Background: Chronic constipation is a prevalent disorder that affects quality of life of patients and consumes resources in healthcare systems worldwide. In clinical practice, it is still considered a challenge as clinicians frequently are unsure as to which treatments to use and when. Over a decade ago, a Neurogastroenterology and Motility journal supplement devoted to the investigation and management of constipation was published (Neurogastroenterol Motil 2009;21(Suppl 2):1). In October 2018, the 3rd London Masterclass, entitled “Contemporary management of constipation” was held. The faculty members of this symposium were invited to write two reviews to present a collective synthesis of talks presented and discussions held during this meeting. The first review addresses epidemiology, diagnosis, clinical associations, pathophysiology, and investigation. Purpose: The present is the second of these reviews, providing contemporary perspectives and clinical challenges regarding behavioral, conservative, medical, and surgical treatments for patients presenting with constipation. It includes a management algorithm to guide clinical practice.

Original languageEnglish (US)
JournalNeurogastroenterology and Motility
DOIs
StateAccepted/In press - 2021

Keywords

  • IBS-C
  • algorithm
  • constipation
  • treatment

ASJC Scopus subject areas

  • Physiology
  • Endocrine and Autonomic Systems
  • Gastroenterology

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