@article{1ae4359140ae43ec87c7a64b2fdf8c62,
title = "Chromosomal mapping of five highly conserved murine homologues of the Drosophila RING finger gene Seven-in-absentia",
abstract = "Seven-in-absentia (sina) is epistatic to all other known genes in the sevenless-ras signaling pathway, which mediates R7 photoreceptor formation in the Drosophila eye. The murine genome contains several closely related sina homologues (Siah1A-D, Siah2) that are also likely to participate in ras signaling. As part of a genetic and biochemical analysis of the mammalian Siah genes, we have used gene-specific probes to map the chromosomal positions of each family member. Here we report their chromosomal positions in relation to a number of known mouse mutations and also describe an analysis of the human Siah genes. By comparing the complexity of the Siah genes in these two mammalian species we have gained further insight into which members of this murine multigene family are likely to be functional.",
author = "Holloway, {Andrew J.} and Della, {Neil G.} and Fletcher, {Colin F.} and Largespada, {David A.} and Copeland, {Neal G.} and Jenkins, {Nancy A.} and Bowtell, {David D.L.}",
note = "Funding Information: We thank Debra J. Gilbert for excellent technical assistance and Susan Boag for collecting human blood samples. Work in Australia was supported by grants from the Howard Hughes Medical Institute, the Wellcome Trust, the Anti-Cancer Council of Victoria, the National Health and Medical Research Council of Australia, and the Potter Foundation. Work in the United States was supported by the National Cancer Institute, DHHS, under contract with ABL. D.B. is a Howard Hughes International Research Scholar and Wellcome Trust Senior Research Fellow in Medical Research in Australia. N.D. and A.H. are the recipients of an NH&MRC Medical Postgraduate Research Scholarship and an Australian Postgraduate Award, respectively. Copyright: Copyright 2017 Elsevier B.V., All rights reserved.",
year = "1997",
month = apr,
day = "15",
doi = "10.1006/geno.1997.4642",
language = "English (US)",
volume = "41",
pages = "160--168",
journal = "Genomics",
issn = "0888-7543",
publisher = "Academic Press",
number = "2",
}