Chromosomal Localization of Mouse Bullous Pemphigoid Antigens, BPAG1 and BPAG2: Identification of a New Region of Homology between Mouse and Human Chromosomes

Neal G. Copeland; Debra J. Gilbert; Kehua Li; Daisuke Sawamura; George J. Giudice; Mon Li Chu; Nancy A. Jenkins; Jouni Uitto

doi:10.1006/geno.1993.1027

Chromosomal Localization of Mouse Bullous Pemphigoid Antigens, BPAG1 and BPAG2: Identification of a New Region of Homology between Mouse and Human Chromosomes

Neal G. Copeland, Debra J. Gilbert, Kehua Li, Daisuke Sawamura, George J. Giudice, Mon Li Chu, Nancy A. Jenkins, Jouni Uitto

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Two bullous pemphigoid antigens, BPAG1 and BPAG2, have been recently cloned and mapped to human chromosomes 6p12-p11 and 10q24.3, respectively. In this study, we localized the corresponding mouse genes by interspecific backcross analysis. Bpag-1 mapped to the proximal region of mouse chromosome 1, identifying a new region of homology between human chromosome 6 and mouse chromosome 1. Bpag-2 mapped to the distal end of mouse chromosome 19 in a region of homology to human chromosome 10q. These assignments confirm and extend the relationships between the human and the mouse chromosomes.

Original language	English (US)
Pages (from-to)	180-181
Number of pages	2
Journal	Genomics
Volume	15
Issue number	1
DOIs	https://doi.org/10.1006/geno.1993.1027
State	Published - Jan 1993

ASJC Scopus subject areas

Genetics

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title = "Chromosomal Localization of Mouse Bullous Pemphigoid Antigens, BPAG1 and BPAG2: Identification of a New Region of Homology between Mouse and Human Chromosomes",

abstract = "Two bullous pemphigoid antigens, BPAG1 and BPAG2, have been recently cloned and mapped to human chromosomes 6p12-p11 and 10q24.3, respectively. In this study, we localized the corresponding mouse genes by interspecific backcross analysis. Bpag-1 mapped to the proximal region of mouse chromosome 1, identifying a new region of homology between human chromosome 6 and mouse chromosome 1. Bpag-2 mapped to the distal end of mouse chromosome 19 in a region of homology to human chromosome 10q. These assignments confirm and extend the relationships between the human and the mouse chromosomes.",

author = "Copeland, {Neal G.} and Gilbert, {Debra J.} and Kehua Li and Daisuke Sawamura and Giudice, {George J.} and Chu, {Mon Li} and Jenkins, {Nancy A.} and Jouni Uitto",

year = "1993",

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doi = "10.1006/geno.1993.1027",

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AU - Copeland, Neal G.

AU - Gilbert, Debra J.

AU - Li, Kehua

AU - Sawamura, Daisuke

AU - Giudice, George J.

AU - Chu, Mon Li

AU - Jenkins, Nancy A.

AU - Uitto, Jouni

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AB - Two bullous pemphigoid antigens, BPAG1 and BPAG2, have been recently cloned and mapped to human chromosomes 6p12-p11 and 10q24.3, respectively. In this study, we localized the corresponding mouse genes by interspecific backcross analysis. Bpag-1 mapped to the proximal region of mouse chromosome 1, identifying a new region of homology between human chromosome 6 and mouse chromosome 1. Bpag-2 mapped to the distal end of mouse chromosome 19 in a region of homology to human chromosome 10q. These assignments confirm and extend the relationships between the human and the mouse chromosomes.

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Chromosomal Localization of Mouse Bullous Pemphigoid Antigens, BPAG1 and BPAG2: Identification of a New Region of Homology between Mouse and Human Chromosomes

Abstract

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