Chromosomal Localization of Mouse Bullous Pemphigoid Antigens, BPAG1 and BPAG2: Identification of a New Region of Homology between Mouse and Human Chromosomes

Neal G. Copeland, Debra J. Gilbert, Kehua Li, Daisuke Sawamura, George J. Giudice, Mon Li Chu, Nancy A. Jenkins, Jouni Uitto

Research output: Contribution to journalArticle

21 Scopus citations

Abstract

Two bullous pemphigoid antigens, BPAG1 and BPAG2, have been recently cloned and mapped to human chromosomes 6p12-p11 and 10q24.3, respectively. In this study, we localized the corresponding mouse genes by interspecific backcross analysis. Bpag-1 mapped to the proximal region of mouse chromosome 1, identifying a new region of homology between human chromosome 6 and mouse chromosome 1. Bpag-2 mapped to the distal end of mouse chromosome 19 in a region of homology to human chromosome 10q. These assignments confirm and extend the relationships between the human and the mouse chromosomes.

Original languageEnglish (US)
Pages (from-to)180-181
Number of pages2
JournalGenomics
Volume15
Issue number1
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Genetics

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