Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization

A. T. Natarajan, Sylvia Vermeulen, F. Darroudi, Marcus B. Valentine, Thomas P. Brent, Sankar Mitra, Keizo Tano

Research output: Contribution to journalArticle

48 Scopus citations


Recombinant lambda phage DNA containing segments of human O6-methylguanine-DNA transferase gene was employed to localize this gene among the human chromosomes using non-radioactive in situ hybridization technique. This gene was found to be present at the telomeric end, 26q, of the long arm of the chromosome 10.

Original languageEnglish (US)
Pages (from-to)83-85
Number of pages3
Issue number1
StatePublished - Jan 1992

ASJC Scopus subject areas

  • Genetics
  • Toxicology
  • Genetics(clinical)
  • Health, Toxicology and Mutagenesis

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