Chromosomal assignment of the heparin-binding cytokine genes MDK and PTN in mouse and man

Bryan O’Hara, N. A. Jenkins, D. J. Gilbert, N. G. Copeland, T. B. Shows, R. L. Eddy, P. Böhlen, I. Kovesdi

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

MDK and PTN are two members of a family of cytokines thought to be involved in a number developmental processes. The locations for these genes in man and mouse using somatic cell hybrid analysis and interspecific backcross analysis. Human MDK was mappede to 11p13→p11. MDK in the mouse (Mdk) was mapped to a syntenic region of mouse Chromosome 2. A pseudogene of Mdk was mapped to mouse Chromosome 11. The closely related human gen PTN was mapped to a seperate location on human chromosome region 7q22→qter.

Original languageEnglish (US)
Pages (from-to)40-43
Number of pages4
JournalCytogenetics and Cell Genetics
Volume69
Issue number1-2
DOIs
StatePublished - 1995

ASJC Scopus subject areas

  • Genetics
  • Cell Biology

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