MDK and PTN are two members of a family of cytokines thought to be involved in a number developmental processes. The locations for these genes in man and mouse using somatic cell hybrid analysis and interspecific backcross analysis. Human MDK was mappede to 11p13→p11. MDK in the mouse (Mdk) was mapped to a syntenic region of mouse Chromosome 2. A pseudogene of Mdk was mapped to mouse Chromosome 11. The closely related human gen PTN was mapped to a seperate location on human chromosome region 7q22→qter.
ASJC Scopus subject areas
- Molecular Biology