Abstract
We present a rare case of a chromophobe renal cell carcinoma that progressed to a high-grade spindle cell sarcoma. The tumor affected a 50-year-old man who had presented with right upper quadrant discomfort and hematuria and subsequently underwent a right radical nephrectomy. Microscopically, the tumor was composed of two distinct components, a chromophobe renal cell carcinoma and a sarcomatoid component. The sarcomatoid component had exhibited aggressive behavior by spreading to a regional lymph node. This case report shows that chromophobe carcinoma can develop a sarcomatoid transformation with a high propensity for invasive growth and metastasis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 296-299 |
| Number of pages | 4 |
| Journal | Annals of Diagnostic Pathology |
| Volume | 7 |
| Issue number | 5 |
| DOIs | |
| State | Published - Jan 1 2003 |
Keywords
- Arcomatoid carcinoma
- Chromophobe carcinoma
- Kidney morphology
ASJC Scopus subject areas
- Pathology and Forensic Medicine
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