Cholesteryl ester and triacylglycerol fatty acids in type V hyperlipidemia

R. G. Jensen, R. M. Clark, S. A. Gerrior, M. B. Fey, Antonio Gotto

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


The fatty acid compositions of plasma cholesteryl esters (CE) and triacylglycerols (TG) from seven healthy individuals and five patients with type V hyperlipoproteinemia were determined. Very low density (VLDL), low density (LDL) and high density lipoproteins (HDL) were isolated. The lipids were extracted from the lipoproteins and the triacylglycerols and cholesteryl esters separated for analysis. The fatty acid compositions of triacylglycerols from healthy and type V individuals were very similar. The cholesteryl esters from type V patients had increased contents of palmitic and decreased amounts of linoleic and arachidonic acids as compared to the normal individuals. The fatty acid composition of the cholesteryl esters from the high density lipoproteins had the greatest deviation. The fatty acid compositions of the triacylglycerols from the two groups were similar. However, the triacylglycerols in all lipoprotein fractions contained more palmitic and oleic and less linoleic and arachidonic acids than the cholesteryl esters.

Original languageEnglish (US)
Pages (from-to)691-694
Number of pages4
Issue number7
StatePublished - Jul 1 1979

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Cell Biology


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