Childhood brain tumor epidemiology: A brain tumor epidemiology consortium review

Kimberly J. Johnson, Jennifer Cullen, Jill S. Barnholtz-Sloan, Quinn T. Ostrom, Chelsea E. Langer, Michelle C. Turner, Roberta McKean-Cowdin, James L. Fisher, Philip J. Lupo, Sonia Partap, Judith A. Schwartzbaum, Michael E. Scheurer

Research output: Contribution to journalReview articlepeer-review

309 Scopus citations

Abstract

Childhood brain tumors are the most common pediatric solid tumor and include several histologic subtypes. Although progress has been made in improving survival rates for some subtypes, understanding of risk factors for childhood brain tumors remains limited to a few genetic syndromes and ionizing radiation to the head and neck. In this report, we review descriptive and analytical epidemiology childhood brain tumor studies from the past decade and highlight priority areas for future epidemiology investigations and methodological work that is needed to advance our understanding of childhood brain tumor causes. Specifically, we summarize the results of a review of studies published since 2004 that have analyzed incidence and survival in different international regions and that have examined potential genetic, immune system, developmental and birth characteristics, and environmental risk factors.

Original languageEnglish (US)
Pages (from-to)2716-2736
Number of pages21
JournalCancer Epidemiology Biomarkers and Prevention
Volume23
Issue number12
DOIs
StatePublished - Dec 1 2014

ASJC Scopus subject areas

  • General Medicine

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